September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.
32 citations
,
January 1990 in “Clinical Endocrinology” Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
13 citations
,
April 2020 in “European Journal of Dermatology” Apremilast showed mixed results for treating severe alopecia areata.
2 citations
,
May 2021 in “Molecules” A new method was created to analyze certain chemicals in the urine of alopecia areata patients, revealing they have higher metanephrine content. This method can also be used for other related diseases.
97 citations
,
January 2006 in “Dermatology” imTA and pulse therapy are effective for alopecia areata with manageable side effects, but relapse rates need improvement.
January 2026 in “Journal of Community Medicine and Health Solutions” PP405 shows promise as a new, effective treatment for hair loss with minimal side effects.
2 citations
,
December 2021 in “BMC veterinary research” Long-term use of difluprednate eye drops in dogs can lead to hair loss and hormone imbalance.
6 citations
,
September 2019 in “Indian Journal of Dermatology” January 2017 in “프로그램북(구 초록집)” 123 citations
,
June 2006 in “Journal of Neurobiology” Progesterone protects brain cells, but Provera does not.
14 citations
,
February 1994 in “Tetrahedron Letters” Adding cerium(III) chloride to Grignard reagents improves the making of compounds that could treat prostate issues and hair loss.
4 citations
,
April 2018 in “Journal of Investigative Dermatology” Hydroxypinacolone retinoate is a potent anti-aging ingredient for skin that is more effective and less irritating than other forms of retinoids.
1 citations
,
April 1987 in “American Journal of Nursing” Some drugs can cause serious side effects, like hypoglycemia from mix-ups, skin reactions, or depression, and while penicillamine may help rheumatoid arthritis more than auranofin, it has more severe side effects.
The treatment changed hormone levels and increased sexual behavior in female capuchin monkeys.
1 citations
,
January 2019 in “Skin Pharmacology and Physiology” Eplerenone, a mineralocorticoid receptor antagonist, was found to promote hair growth in human hair follicles.
9 citations
,
January 2009 in “PubMed” Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.
1 citations
,
December 1971 in “PubMed”
5 citations
,
March 2005 in “Journal of The American Academy of Dermatology” May 2008 in “Trends in Urology Gynaecology & Sexual Health” Loop diuretics may double bone loss in elderly men, finasteride lowers prostate cancer risk but may increase high-grade tumors, abarelix reduces testosterone quickly, and transdermal testosterone offers minimal sexual benefit for women.
March 2019 in “Reactions Weekly”
42 citations
,
May 2003 in “Mini-reviews in Medicinal Chemistry” New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
14 citations
,
January 2016 in “Annals of dermatology/Annals of Dermatology” Oral cyclosporine is more effective and safer than betamethasone for treating alopecia areata.
68 citations
,
April 2002 in “Journal of Alternative and Complementary Medicine” Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.
7 citations
,
April 1992 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Women with non-classical congenital adrenal hyperplasia have higher levels of certain steroids, which can be reduced by treatment.
June 2023 in “International journal of pharmaceutical quality assurance” Eclipta alba extract could be a promising natural treatment for hair loss.
149 citations
,
June 2002 in “Veterinary record/The veterinary record” Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.
January 1999 in “Salina: revista de lletres” Ashwagandha may help reduce symptoms of adrenal hyperplasia.
31 citations
,
September 2014 in “International Journal of Dermatology” Anthralin is effective for psoriasis and alopecia with minimal systemic side effects but can irritate the skin.
2 citations
,
December 2001 in “Dermatologic Therapy” Steroids may not work well for alopecia areata because of high unoccupied receptors and low thioredoxin levels.