130 citations
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February 2018 in “Journal of Investigative Dermatology” Tofacitinib may help treat severe hair loss, but more research is needed.
128 citations
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February 2016 in “British Journal of Dermatology” Alopecia areata significantly lowers the quality of life, especially in emotional and mental health aspects.
122 citations
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November 1984 in “Journal of the American Academy of Dermatology” No single treatment is consistently effective for alopecia areata, and more research is needed.
117 citations
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February 1996 in “International Journal of Dermatology” A 300 mg monthly pulse of prednisolone effectively and safely treats widespread alopecia areata.
114 citations
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October 2006 in “Journal of the European Academy of Dermatology and Venereology” The new clobetasol propionate foam is effective and safe for treating alopecia areata.
114 citations
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August 2002 in “Journal of Investigative Dermatology” Alopecia areata is caused by an immune response, and targeting immune cells might help treat it.
109 citations
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May 2011 in “Dermatologic Therapy” Alopecia areata is a type of hair loss that can lead to complete baldness, often associated with other autoimmune conditions, and half of the cases may see hair return within a year.
109 citations
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November 1987 in “Archives of dermatology” Anthralin cream helped 25% of patients with severe alopecia areata regrow hair, but caused skin irritation.
106 citations
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January 2013 in “Clinical and Developmental Immunology” Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.
105 citations
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March 2014 in “British journal of dermatology/British journal of dermatology, Supplement” Alopecia areata patients often have low vitamin D levels, suggesting they might benefit from vitamin D supplements.
105 citations
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December 1995 in “British journal of dermatology/British journal of dermatology, Supplement” PUVA treatment is generally ineffective for alopecia areata.
104 citations
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March 1987 in “Journal of The American Academy of Dermatology” Minoxidil helps hair growth in 63.6% of alopecia patients, with 27.3% having excellent results.
101 citations
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November 1992 in “Archives of Dermatology” Steroids help hair regrowth, and minoxidil slows post-steroid hair loss, but effects are temporary.
101 citations
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March 1987 in “Journal of The American Academy of Dermatology” Minoxidil solution helps hair regrowth in alopecia areata, with 5% being more effective.
100 citations
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July 2018 in “Journal of The American Academy of Dermatology” People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.
100 citations
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July 2006 in “British Journal of Dermatology” Triamcinolone acetonide injections help hair regrow quickly in mild alopecia but not in severe cases.
97 citations
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January 2006 in “Dermatology” imTA and pulse therapy are effective for alopecia areata with manageable side effects, but relapse rates need improvement.
95 citations
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November 2018 in “Australasian journal of dermatology” Alopecia areata treatment varies, with no optimal method established yet.
95 citations
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July 2016 in “Journal of The American Academy of Dermatology” People with alopecia areata, a skin disease, generally have a poor quality of life, especially if more of their scalp is affected.
95 citations
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June 2002 in “The Journal of Dermatology” Onion juice is more effective than tap water for hair re-growth in patchy alopecia areata.
91 citations
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May 2023 in “Journal of Cutaneous Medicine and Surgery” Alopecia Areata affects 2% globally, with treatments like essential oils, garlic, and JAK inhibitors showing promise, but more research is needed.
91 citations
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March 1996 in “Archives of Dermatological Research” Certain cytokines and growth factors can inhibit hair growth and may affect alopecia areata.
89 citations
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August 2018 in “JAMA Dermatology” Contact immunotherapy can improve hair regrowth in alopecia areata patients.
89 citations
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October 1996 in “Dermatologic Clinics” Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
87 citations
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December 2016 in “British journal of dermatology/British journal of dermatology, Supplement” Cancer patients treated with immune checkpoint inhibitors may develop alopecia, but some hair regrowth is possible with treatment.
86 citations
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January 2020 in “British Journal of Dermatology” The AA-IGA scale reliably measures treatment success in alopecia areata by considering both clinician and patient views.
86 citations
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December 2002 in “Tissue Antigens” A specific gene change is linked to severe hair loss.
85 citations
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November 2004 in “Journal of the American Academy of Dermatology” The 308-nm excimer laser helps hair regrowth in some alopecia areata cases but not all.
84 citations
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August 1991 in “British Journal of Dermatology” Most children treated with diphencyprone regrew some or all of their hair.
83 citations
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June 2017 in “Journal of the American Academy of Dermatology” Topical JAK inhibitors may help children with alopecia areata regrow hair.