788 citations
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February 2007 in “Nature” The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
532 citations
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August 2011 in “Journal of the American Academy of Dermatology” Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.
370 citations
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September 1999 in “The New England Journal of Medicine” Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.
277 citations
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July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
271 citations
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May 2019 in “Cells” The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.
249 citations
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November 2003 in “Clinical endocrinology” Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
232 citations
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June 1975 in “Journal of Steroid Biochemistry” Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.
184 citations
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August 1983 in “The journal of pediatrics/The Journal of pediatrics” Biotinidase deficiency has various symptoms and can be treated with biotin supplements.
178 citations
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December 2011 in “Journal of Dermatological Case Reports” Trichoscopy is a useful tool for diagnosing different hair and scalp diseases by their unique visual features.
157 citations
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June 2011 Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.
138 citations
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November 2015 in “Journal of Pharmacology and Experimental Therapeutics” Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
124 citations
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December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
109 citations
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September 2011 in “Human molecular genetics online/Human molecular genetics” New treatments targeting specific genes show promise for treating keratin disorders.
105 citations
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September 1995 in “Journal of The American Academy of Dermatology” Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.
103 citations
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March 2015 in “Nature Communications” A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.
87 citations
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July 2018 in “Nursing Clinics of North America” PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.
87 citations
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February 2009 in “PubMed” Alopecia in captive primates can be caused by many factors, so thorough testing is needed before blaming stress.
86 citations
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August 2014 in “Journal of The American Academy of Dermatology” To diagnose hair loss, use a systematic approach including history, exams, and tests.
85 citations
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June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.
85 citations
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February 1989 in “Journal of The American Academy of Dermatology” Children with loose anagen hair have easily pluckable hair due to root sheath problems, and it might improve without treatment.
77 citations
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June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.
75 citations
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May 2013 in “Journal of the American Academy of Dermatology” Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.
68 citations
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March 1965 in “The BMJ” Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.
62 citations
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January 2015 in “Journal of Dermatological Science” New genetic discoveries may lead to better treatments for alopecia areata.
62 citations
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January 2010 in “Hormone research in paediatrics” Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.
60 citations
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October 2014 in “Journal of the American Academy of Dermatology” Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.
60 citations
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September 2010 in “Journal of the American Academy of Dermatology” Small white dots on the scalp seen with a dermoscope correspond to sweat ducts and vary with different hair disorders.
58 citations
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October 2001 in “Dermatologic Clinics” Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.
54 citations
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November 1986 in “Journal of the American Academy of Dermatology” Generalized trichoepitheliomas with hair loss may indicate myasthenia gravis.
54 citations
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October 2019 in “Australian Journal of General Practice” Accurate diagnosis and treatment are crucial for managing superficial fungal infections, with terbinafine being the best oral treatment for nail infections.