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Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Finasteride exposure harms tadpole reproduction and hormone balance.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Pueraria mirifica extract may help treat benign prostatic hyperplasia.

Dutasteride may help shrink prostate cancer tumors.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Finasteride negatively affects fish reproduction and gonadal development.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

Finasteride helps protect brain in old male rats.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

Finasteride may cause kidney damage.

Alpha Lipoic Acid helps protect skin from smoking damage.

Finasteride effectively treats male hair loss, improving growth and density.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

Testosterone pellet therapy may better address hormone imbalances in aging by focusing on local hormone production and symptom relief.

Ferulic acid may help hair grow by activating certain receptors in cells.

A new compound was made that might help treat diseases related to male hormones.