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Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite

research Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite

39 citations , April 2007 in “Therapeutic Drug Monitoring”

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

research Human genetic basis of coronavirus disease 2019

38 citations , September 2021 in “Signal Transduction and Targeted Therapy”

Genetic differences affect COVID-19 severity and treatment development.

Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models

research Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models

38 citations , June 2018 in “Archives of Toxicology”

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

research Deciphering the functions of the hair follicle infundibulum in skin physiology and disease

38 citations , September 2014 in “Cell and Tissue Research”

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

research Adult skin acute stress responses to short‐term environmental and internal aggression from exposome factors

37 citations , June 2021 in “Journal of the European Academy of Dermatology and Venereology”

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

research Intravaginal Testosterone Improves Sexual Satisfaction and Vaginal Symptoms Associated With Aromatase Inhibitors

37 citations , September 2018 in “The Journal of Clinical Endocrinology and Metabolism”

Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.

Body Composition Changes and Inhibition of Fat Development In Vivo Implicate Androgen in Regulation of Stem Cell Lineage Allocation

research Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation

37 citations , June 2011 in “Journal of Cellular Biochemistry”

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

research Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin

36 citations , January 2019 in “Nature communications”

High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.

Vasoactive Intestinal Peptide, Whose Receptor-Mediated Signaling May Be Defective in Alopecia Areata, Provides Protection from Hair Follicle Immune Privilege Collapse

research Vasoactive intestinal peptide, whose receptor-mediated signalling may be defective in alopecia areata, provides protection from hair follicle immune privilege collapse

36 citations , April 2016 in “British journal of dermatology/British journal of dermatology, Supplement”

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

Effect of Finasteride on Behavioral Arousal and Somatosensory Evoked Potentials in Fetal Sheep

research Effect of finasteride on behavioural arousal and somatosensory evoked potentials in fetal sheep

36 citations , June 2001 in “Neuroscience Letters”

Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.

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