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Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

A new, efficient method was developed to synthesize a specific compound and its derivatives.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Testosterone is made by Leydig cells, is active when not bound to proteins, and works by binding to receptors in muscles and other tissues.

New progesterone-based compounds can block male hormones.

New compounds show promise as nonsteroidal treatments for hair loss.

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

Dihydrotestosterone (DHT) and its active metabolites play a key role in various diseases, and the development of 5α-reductase inhibitors can help treat these conditions.

Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.

Neurosteroids may help treat disorders with too much dopamine activity.

Some sports supplements can cause health issues like mood swings, hair loss, and heart problems in men.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.

Anti-androgen drugs can treat conditions like prostate cancer and male pattern baldness by blocking effects of testosterone and DHT.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.

Therapies targeting the androgen receptor are being developed to treat prostate cancer and improve bone and muscle health.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.

Androgens are essential for maintaining adult neuromuscular structure.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.