research Role of Anti-Androgens in the Management of Polycystic Ovary Syndrome (PCOS)
Anti-androgens help manage PCOS symptoms like excess hair and acne.
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research Role of Anti-Androgens in the Management of Polycystic Ovary Syndrome (PCOS)
Anti-androgens help manage PCOS symptoms like excess hair and acne.
research Urinary steroids in women with androgenic alopecia
Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.
research The biology of androgenetic alopecia
research Blockade of Androgen Markers Using a Novel Betasitosterol, Thioctic Acid and Carnitine-containing Compound in Prostate and Hair Follicle Cell-based Assays
The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.
research The challenging role of antiandrogens in the management of polycystic ovary syndrome
Antiandrogens are used to manage polycystic ovary syndrome by reducing androgen levels or controlling their effects, often combined with lifestyle changes and other treatments.
research Silencing the androgen receptor: New skills for antiandrogen oligonucleotide skin and hair therapy
Targeting androgen receptors with antiandrogen oligonucleotides could effectively treat hair loss.
research Intermolecular NH2-/Carboxyl-terminal Interactions in Androgen Receptor Dimerization Revealed by Mutations That Cause Androgen Insensitivity
Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.
research Epitestosterone—an endogenous antiandrogen?
Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.
research Defects in Androgen Biosynthesis Causing 46,XY Disorders of Sexual Development
Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.
research Synthesis of mimics of steroid A ring as potential enzyme inhibitors
Mimicking the steroid A-ring may help create effective enzyme inhibitors for prostate disease treatment.
research Androgen Resistance Associated With a Qualitative Abnormality of the Androgen Receptor and Responsive to High Dose Androgen Therapy*
High-dose androgen therapy can help manage certain types of androgen resistance.
research Androgenetic alopecia.
research Synthesis and Study of Some 17a-aza-D-homo Steroids as 5α-Reductase Inhibitors
The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.
research Testosterone, cytochrome P450, and cardiac hypertrophy
Heart-specific steroid metabolism is crucial in cardiac hypertrophy.
research Protective trend of anti-androgen therapy during the COVID-19 pandemic: A meta-analysis
Anti-androgen therapy might help protect against COVID-19 infection and reduce death risk.
research Why steroids may not always work in alopecia areata: elevated unoccupied glucocorticoid receptors and decreased levels of thioredoxin
Steroids may not work well for alopecia areata because of high unoccupied receptors and low thioredoxin levels.
research Androgens Regulate Tau Phosphorylation Through Phosphatidylinositol 3-Kinase–Protein Kinase B–Glycogen Synthase Kinase 3β Signaling
research ANTI‐ANDROGENS IN HIRSUTISM
Cyproterone acetate effectively treats hirsutism and related conditions.
research Effect of flutamide and two novel synthetic steroids on GABA, glutamine and some oxidative stress markers in rat brain and prostate
Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.
research Higher Levels of Steroidogenic Acute Regulatory Protein and Type I 3β-Hydroxysteroid Dehydrogenase in the Scalp of Men with Androgenetic Alopecia
Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.
research Endocrine and Intracrine Sources of Androgens in Women: Inhibition of Breast Cancer and Other Roles of Androgens and Their Precursor Dehydroepiandrosterone
Androgens and DHEA can help prevent breast cancer and improve health in women.
research Androgenic effect of testosterone and some of its metabolites in relation to their biotransformation in the skin.
Testosterone and some of its forms can strongly stimulate oil gland growth in skin.
research GC-MS determination of steroids related to androgen biosynthesis in human hair with pentafluorophenyldimethylsilyl–trimethylsilyl derivatisation
The method accurately measures certain steroids in human hair, showing different levels in males and females.
research Design, synthesis and biological evaluation of novel 3-oxo-4-oxa-5α-androst-17β-amide derivatives as dual 5α-reductase inhibitors and androgen receptor antagonists
New compounds were made that are promising for prostate cancer therapy.
research Steroidogenesis in steroid related cancers
Steroid-producing capabilities in certain cancers may contribute to treatment resistance.
research Machine learning-based steroid metabolome analysis reveals three distinct subtypes of polycystic ovary syndrome and implicates 11-oxygenated androgens as major drivers of metabolic risk
PCOS has three subtypes, with 11-oxygenated androgens increasing metabolic risk.
research Thiohydrazides in the Synthesis of Functionalized Extranuclear Heterosteroids
New steroid derivatives show promise as anticancer agents, even against resistant cells.
research ANDROGEN METABOLISM AS IT AFFECTS HAIR GROWTH IN ANDROGENETIC ALOPECIA
Androgens, like DHT, affect hair growth and treatments like finasteride may help.
research SUN-118 A Case of Anastrozole Induced Hyperandrogenism
Anastrozole can cause increased testosterone, leading to symptoms like hair growth and thinning.