research Targeting lymphoid-derived IL-17 signaling to delay skin aging
Blocking IL-17 signaling may reduce skin inflammation and delay aging.
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research An In Vivo Mouse Excisional Wound Model of Scarless Healing
Mice healed without scars as fetuses but developed scars as adults, suggesting scarless healing might be replicated with further research.
research Prevascularization of dermal substitutes with adipose tissue-derived microvascular fragments enhances early skin grafting
Using adipose tissue-derived fragments improves early skin graft success.
research Recent advances in nanocarrier-loaded gels: Which drug delivery technologies against which diseases?
Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.
research Midazolam Ameliorates the Behavior Deficits of a Rat Posttraumatic Stress Disorder Model through Dual 18 kDa Translocator Protein and Central Benzodiazepine Receptor and Neurosteroidogenesis
Midazolam reduces PTSD-like behavior in rats by acting on specific brain receptors.
research Ablative Fractional Resurfacing in Topical Drug Delivery: An Update and Outlook
Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.
research Hair-Growth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms
Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.
research Persistent erectile dysfunction in men exposed to the 5α-reductase inhibitors, finasteride, or dutasteride
Using finasteride or dutasteride may cause long-lasting erectile dysfunction.
research The Pharmacologic Treatment of Muscle Pain
The document concludes that more research is needed to understand how to treat muscle pain with drugs.
research Micro-Needling Depth Penetration, Presence of Pigment Particles, and Fluorescein-Stained Platelets: Clinical Usage for Aesthetic Concerns
Micro-needling effectively improves wrinkles, scars, and hair growth, but proper technique and safety are important.
research A nude mouse model of hypertrophic scar shows morphologic and histologic characteristics of human hypertrophic scar
Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
research Complications of Rhytidectomy
Face-lifts can lead to complications like bleeding, nerve injury, skin death, hair loss, and rare infections, with careful surgery reducing risks.
research Recent Progress in Prostaglandin F2αEthanolamide (Prostamide F2α) Research and Therapeutics
New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.
research Protective effects of melatonin against metabolic and reproductive disturbances in polycystic ovary syndrome in rats
Melatonin may help treat PCOS symptoms in rats.
research The nocebo effect: A clinicians guide
Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.
research Hydrogen peroxide disrupts scarless fetal wound repair
Hydrogen peroxide can cause scars by changing healing processes and increasing certain protein levels.
research The prolactin receptor as a therapeutic target in human diseases: browsing new potential indications
Blocking the prolactin receptor might help treat various diseases, but more research is needed.
research Multiple crosslinked, self-healing, and shape-adaptable hydrogel laden with pain-relieving chitosan@borneol nanoparticles for infected burn wound healing
The hydrogel effectively treats infected burn wounds by reducing pain and preventing infection.
research LabeledIn: Cataloging labeled indications for human drugs
Researchers created LabeledIn, a detailed list of drug uses, showing the importance of human input in making such lists.
research Effect of non-steroidal anti-inflammatory drugs on post-surgical complications against the backdrop of the opioid crisis
NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.
research Skin disease in pregnancy
Pregnancy can change skin disease severity, with some conditions improving and others worsening, and treatment should balance benefits and fetal safety.
research Alteration of Ethanol Drinking in Mice via Modulation of the GABAA Receptor with Ganaxolone, Finasteride, and Gaboxadol
Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.
research Middle East Medicinal Plants in the Treatment of Diabetes: A Review
Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.
research Sex hormones modulate pathogenic processes in experimental traumatic brain injury
Sex hormones affect brain injury differently in males and females.
research Resveratrol derivatives: a patent review (2009 – 2012)
New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
research Signalling by senescent melanocytes hyperactivates hair growth
Senescent melanocytes can boost hair growth by activating hair stem cells.
research Interaction between stem cell factor and endothelin-1: effects on melanogenesis in human skin xenografts
SCF and ET-1 together significantly increase skin pigmentation and melanin production.
research The anxiolytic effect of pregnancy in rats is reversed by finasteride
Pregnancy reduces anxiety in rats, but finasteride reverses this effect.
research Physical methods for topical skin drug delivery: concepts and applications
New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
research Dermatological Manifestations of Stress in Normal and Psychiatric Populations
Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.