research The Hair Follicle: A Paradoxical Androgen Target Organ
Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.
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research Clinical, metabolic, and endocrine parameters in response to metformin and lifestyle intervention in women with polycystic ovary syndrome: A randomized, double-blind, and placebo control trial
Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.
research Functional complexity of hair follicle stem cell niche and therapeutic targeting of niche dysfunction for hair regeneration
Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
research Male pattern hair loss: current understanding
Genetics and hormones cause hair loss; finasteride treats it safely.
research Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells
High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
research Cutaneous Findings and Systemic Associations in Women With Polycystic Ovary Syndrome
Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.
research Increased Androgen Binding Capacity in Sebaceous Glands in Scalp of Male-pattern Baldness
Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.
research Polycystic Ovary Syndrome: A Common But Often Unrecognized Condition
Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.
research Polymeric nanoparticles-embedded organogel for roxithromycin delivery to hair follicles
Scientists created a gel with nanoparticles to deliver medicine to hair follicles effectively.
research The biology of hair diversity
Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.
research Testosterone therapy for sexual dysfunction in postmenopausal women
Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.
research Biology of Hair Growth
Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.
research Anti-androgenic effect of sesquiterpenes isolated from the rhizomes of Curcuma aeruginosa Roxb.
Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.
research Malignancy and Cancer Treatment-Related Hair and Nail Changes
Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.
research Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% piroctone olamine and 1% zinc pyrithione formulations
All three shampoos reduced dandruff and hair loss, but ketoconazole and piroctone olamine also made hair thicker.
research Insulin resistance and obesity among infertile women with different polycystic ovary syndrome phenotypes
Women with PCOS are more likely to have insulin resistance and obesity, especially those with the most severe type I PCOS.
research Polycystic Ovary Syndrome and Its Differential Diagnosis
The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.
research PNU 157706, a novel dual type I and II5α-reductase inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
research No Evidence that 2D:4D is Related to the Number of CAG Repeats in the Androgen Receptor Gene
Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.
research Aging in hair follicle stem cells and niche microenvironment
Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
research The hair cycle and its regulation
Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.
research Recent advances in thiasteroids chemistry
New sulfur-containing steroid analogs show promise for more targeted medical treatments.
research When should an insulin sensitizing agent be used in the treatment of polycystic ovary syndrome?
Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.
research ANTIANDROGEN THERAPY IN DERMATOLOGY
Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research HSD3B1 Genotypes Conferring Adrenal-Restrictive and Adrenal-Permissive Phenotypes in Prostate Cancer and Beyond
Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.
research Effects of Finasteride (1 mg) on Hair Transplant
Finasteride improves surrounding scalp hair and increases hair density after hair transplant.
research Platelet-Rich Plasma for the Aesthetic Surgeon
Platelet-Rich Plasma (PRP) shows promise for hair growth and skin improvement in aesthetic surgery.
research Hormone und Haarwachstum
Different hormones affect hair growth and conditions, with some causing hair loss and others promoting it.
research Effects of Finasteride (1 mg) on Hair Transplant
Finasteride improves surrounding scalp hair and increases hair density after hair transplant.