January 1995 in “Adolescent and pediatric gynecology” Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.
182 citations
,
June 2002 in “Journal of Neuroscience” Androgens can help prevent memory problems caused by apoE4.
66 citations
,
January 2000 in “Hormone Research in Paediatrics” Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.
12 citations
,
June 2013 in “The Prostate” Dutasteride and finasteride affect different cell types differently.
9 citations
,
March 1991 in “Endocrinology” Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.
165 citations
,
December 2002 in “Molecular and Cellular Endocrinology” Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
134 citations
,
April 2020 in “Journal of Cosmetic Dermatology” Male pattern hair loss could hint at androgens affecting COVID-19 severity.
71 citations
,
April 2020 in “Journal of Cosmetic Dermatology” Genetic differences may affect COVID-19 deaths; anti-androgens could be potential treatment.
60 citations
,
February 2013 in “Cell reports” The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.
47 citations
,
October 2016 in “Molecular and Cellular Endocrinology” Androgens prevent hair growth by changing Wnt signals in cells.
39 citations
,
March 2018 in “Archives of Dermatological Research” Androgens may block hair growth signals, targeting this could treat hair loss.
37 citations
,
June 2011 in “Journal of Cellular Biochemistry” Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
19 citations
,
November 2012 in “Journal of Dermatological Treatment” Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.
15 citations
,
January 1998 in “Journal of Clinical Periodontology” Finasteride helps treat hair loss by blocking enzyme activity.
9 citations
,
September 2014 in “Cancer Epidemiology, Biomarkers & Prevention” Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.
5 citations
,
December 2021 in “Physiological Research” Men, particularly those with hair loss, are more likely to get the virus, and those with prostate cancer may have milder symptoms. Testosterone's role in the disease is unclear, and the virus doesn't seem to harm male fertility. Women with PCOS might be at higher risk. More research is needed.
1 citations
,
September 2022 in “Problems of Endocrinology” Dutasteride shows promise as a potential treatment for Parkinson's disease.
December 2022 in “Urology Herald” Hormonal status from androgen deprivation therapy may affect COVID-19 severity in men.
88 citations
,
February 2011 in “Journal of Dermatological Science” Minoxidil helps hair growth by activating the β-catenin pathway.
54 citations
,
April 2010 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
31 citations
,
September 2006 in “The Journal of Clinical Endocrinology & Metabolism” Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.
24 citations
,
March 2002 in “Expert opinion on investigational drugs” Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.
5 citations
,
January 1984 in “Journal of psychosomatic obstetrics and gynecology/Journal of psychosomatic obstetrics and gynaecology” The treatment reduced hair growth and testosterone in women with excess hair and had some effects on stress responses.
16 citations
,
October 2007 in “Andrologia” DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
14 citations
,
March 2023 in “Scientific Reports” Oxidative stress, not insulin resistance, is significantly related to free androgen index in PCOS.
30 citations
,
December 2018 in “International Journal of Biological Macromolecules” Chitosan and surface-deacetylated chitin nanofibers may help treat hair loss.
12 citations
,
August 2017 in “Pharmaceutical medicine” Most doctors know the thrombosis risk with Cyproterone/Ethinylestradiol, but some lack details on less common risks and patient instructions; educational materials are underused but useful.
3 citations
,
March 2016 in “Phytotherapy Research” The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.
April 2017 in “Journal of Investigative Dermatology” PRC1 influences skin stem cell development by both turning genes on and off, affecting hair growth and skin cell types.
113 citations
,
November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.