Search

everythinglearnresearchcommunity

for

Search:↓

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.

Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.

Blocking androgen receptors early in life increases estrogen levels and reduces sexual motivation in male rats.

Gut bacteria can lower androgen levels in male mice.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

Women also use 5α-reductase inhibitors for hair loss and hirsutism.

Castration significantly reduces prostate size and BPH symptoms.

Goserelin and oestradiol treatment slightly improved hairiness but did not significantly change sebum production or hair characteristics in mildly hirsute women.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Androgens can help prevent memory problems caused by apoE4.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Women with greater androgen sensitivity respond better to finasteride for hair loss.

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

Pre-operative hormone treatment for hypospadias surgery might improve outcomes, but more research is needed to confirm.

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.

Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.

Neurosteroids like neuro-estrogen and neuro-androgen are crucial for brain function and can improve cognition and protect against aging-related decline.

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

The patient's high testosterone was reduced by a medication that suppresses gonadotropin.

Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.