67 citations
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August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Androgens promote beard growth but cause hair loss in androgenetic alopecia, with TGF-β1 as a potential treatment target.
65 citations
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May 2006 in “Journal of Investigative Dermatology” Dexamethasone may influence hair growth by altering estrogen receptor activity in hair cells.
64 citations
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August 2019 in “Circulation” ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.
63 citations
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December 2013 in “PLoS ONE” Finasteride may reduce prostate cancer spread by lowering certain enzyme levels.
60 citations
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September 1979 in “Fertility and sterility” Spironolactone can reduce hair growth in women with hirsutism.
59 citations
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September 2007 in “Biochemical and Biophysical Research Communications” The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.
59 citations
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August 2004 in “Human Reproduction Update” Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.
57 citations
,
April 2009 in “The Journal of Steroid Biochemistry and Molecular Biology” Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.
54 citations
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July 2002 in “Clinical and Experimental Dermatology” DHT, a testosterone byproduct, causes male pattern baldness.
52 citations
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January 1995 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.