Search

everythinglearnresearchcommunity

for

Search:↓

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Excess maternal androgens can cause heart problems in offspring.

The mouse models are effective for testing new hair loss treatments.

AKR1C3 could be a treatment target for metabolic issues in PCOS.

Ferulic acid may help hair grow by activating certain receptors in cells.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

A certain genetic variation is linked to a higher risk of polycystic ovarian syndrome.

Human scalp hair follicles have PGE2 and its receptors, which might affect hair growth.

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.

Anti-androgens, like finasteride, dutasteride, and spironolactone, may lessen the severity of COVID-19 in men, leading to fewer ICU admissions.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.