research Allopregnanolone is required for prepulse inhibition deficits induced by D1 dopamine receptor activation
Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
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research Effects of in Utero Exposure to Finasteride on Androgen-Dependent Reproductive Development in the Male Rat
Exposure to finasteride in the womb caused lasting reproductive issues in male rats.
research Antiandrogens and Androgen Inhibitors
Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
research Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia
Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
research Blockade of Androgen Markers Using a Novel Betasitosterol, Thioctic Acid and Carnitine-containing Compound in Prostate and Hair Follicle Cell-based Assays
The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.
research The role of mutations on gene AR, in androgenetic alopecia syndrome
Mutations in the AR gene cause hair thinning and loss.
research The challenging role of antiandrogens in the management of polycystic ovary syndrome
Antiandrogens are used to manage polycystic ovary syndrome by reducing androgen levels or controlling their effects, often combined with lifestyle changes and other treatments.
research The Relationship of the 2nd: 4th Digit Ratio to the Maxillary Sinus Volume in Men
Men with lower 2nd to 4th finger ratios tend to have larger sinus volumes.
research Role of anabolic agents in colorectal carcinogenesis: Myths and realities (Review)
The link between anabolic agents and colorectal cancer risk is unclear.
research The AR/miR-221/IGF-1 pathway mediates the pathogenesis of androgenetic alopecia
A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.
research Male pattern baldness: an update.
Male pattern baldness is a genetic condition causing hair loss, with limited but improving treatment options.
research Role of vitamin D and insulin resistance in polycystic ovary syndrome
Vitamin D helps improve PCOS by aiding insulin function and ovarian health.
research Pharmacological Approaches to Controlling Cardiometabolic Risk in Women with PCOS
Treatments for PCOS aim to reduce androgen levels and improve insulin sensitivity to lower cardiometabolic risk.
research Proteolysis‐targeting chimeras in cancer therapy: Targeted protein degradation for next‐generation treatment
PROTACs offer a new, precise way to treat cancer by breaking down harmful proteins.
research Bicalutamide in Dermatology: A Narrative Review
Bicalutamide may effectively treat female pattern hair loss with minimal side effects.
research Anabolic androgenic steroids and carcinogenicity focusing on Leydig cell: a literature review
Anabolic androgenic steroids can increase cancer risk and disrupt hormones.
research Epigenetic modifications may explain the relative protection of occipital hair follicles from androgenetic alopecia in men
Epigenetic changes might protect occipital hair from male pattern baldness.
research Тіе Modern treatment of androgenetic alopecia
Hair loss can be treated with common methods like minoxidil and finasteride, but new potential treatments include growth factors, cytokines, and platelet-rich plasma injections.
research Genetic Markers of Male and Female Pattern Hair Loss
Genetic differences in hair loss can help improve diagnosis and treatment.
research Use of oral contraceptives in the management of acne
Oral contraceptives can help manage acne by reducing androgen levels.
research Methodologic considerations in evaluating early clinical outcomes of GT20029 for androgenetic alopecia
GT20029 showed some hair growth improvement, but longer studies are needed for better results.
research Genetic Insights into Acne, Androgenetic Alopecia, and Alopecia Areata: Implications for Mechanisms and Precision Dermatology
Genetic insights can lead to personalized treatments for acne, androgenetic alopecia, and alopecia areata.
research Abordagens psicológicas e novas terapêuticas perante as escolhas do paciente portador da Síndrome de Morris
Patients with Complete Androgen Insensitivity Syndrome need psychological support and multidisciplinary care for complex treatment decisions.
research Андроген-опосередковані й андрогенонезалежні причини алопеції та акне в жінок. Огляд літератури
Alopecia and acne in women are complex conditions needing coordinated care and personalized treatment.
research Molecular docking study of phytochemical compounds from Kustakudori ennai as a potential anti-alopecia treatment
Certain compounds from Kushtakudori ennai may help treat hair loss.
research Тіе Modern treatment of androgenetic alopecia
New treatments for common hair loss might be safer and more effective than current options.
research Hormonal Effects on Hair Follicles
Hormones like testosterone and estrogen significantly affect hair growth and structure.
research Hyaluronic acid-FGF2-derived peptide bioconjugates for suppression of FGFR2 and AR simultaneously as an acne antagonist
The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.
research Anti-Alopecia Activity of Alkaloids Group from Noni Fruit against Dihydrotestosterone-Induced Male Rabbits and Its Molecular Mechanism: In Vivo and In Silico Studies
Noni fruit extract, specifically the FEA-3 sub-fraction, can increase hair growth and reduce baldness in male rabbits, potentially acting like common hair loss treatments.
research Identification of A p300–SP1–BRD4 Transcriptional Axis as a Key Driver of AR Hyperactivation in Polycystic Ovarian Syndrome
Targeting the p300/AR axis may help treat polycystic ovary syndrome.