research An Update on Plant Derived Anti-Androgens
Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.
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research Eph Receptors and Ephrins: Therapeutic Opportunities
Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.
research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
research American Association of Clinical Endocrinologists, American College of Endocrinology, and Androgen Excess and PCOS Society Disease State Clinical Review: Guide to the Best Practices in the Evaluation and Treatment of Polycystic Ovary Syndrome - Part 1
The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.
research Adverse health effects of androgen use
Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
research Safety aspects of androgen treatment with 5α-dihydrotestosterone
DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
research Local synthesis and function of neuro-estrogen and neuro-androgen: impact on the hippocampus-related cognition and neuronal plasticity
Neurosteroids like neuro-estrogen and neuro-androgen are crucial for brain function and can improve cognition and protect against aging-related decline.
research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
research 46,XY DSD due to impaired androgen production
Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
research Roles of tumor suppressors in regulating tumor-associated inflammation
Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.
research Unchanged androgen-binding properties of sex hormone-binding globulin in male patients with liver cirrhosis
SHBG binding properties are unchanged in male liver cirrhosis patients.
research Controversies Regarding Transdermal Androgen Therapy in Postmenopausal Women
Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.
research Melatonin membrane receptors in peripheral tissues: Distribution and functions
Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
research Anti-androgen Treatments
For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.
research Potential Involvement of the Stem Cell Factor Receptor c-kit in Alopecia Areata and Androgenetic Alopecia: Histopathological, Immunohistochemical, and Semiquantitative Investigations
c-kit affects hair growth and color in alopecia areata and androgenetic alopecia.
research Spontaneous fertility in a male patient with testotoxicosis despite suppression of FSH levels
A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.
research Blockade of Androgen Markers Using a Novel Betasitosterol, Thioctic Acid and Carnitine-containing Compound in Prostate and Hair Follicle Cell-based Assays
The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.
research Maternal PPARγ protects nursing neonates by suppressing the production of inflammatory milk
A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.
research CD4+CD25+FoxP3+ Regulatory Tregs inhibit fibrocyte recruitment and fibrosis via suppression of FGF-9 production in the TGF-β1 exposed murine lung
Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.
research Physiopathology and current treatments of androgenetic alopecia: Going beyond androgens and anti‐androgens
Hair loss treatments work better with lifestyle changes.
research miR-195-5p Regulates Hair Follicle Inductivity of Dermal Papilla Cells by Suppressing Wnt/β-Catenin Activation
miR-195-5p reduces hair growth ability in cells by blocking a specific growth signal.
research Inhibitory Effects of Polyacetylene Compounds from <i>Panax ginseng</i> on Neurotrophin Receptor-Mediated Hair Growth
Certain compounds from Panax ginseng can block proteins that affect hair growth, potentially helping treat hair loss.
research Targeted transfollicular delivery of artocarpin extract from Artocarpus incisus by means of microparticles
Microparticles containing artocarpin extract could effectively treat hair loss and acne with minimal side effects.
research Androgenic disorders
The book is a valuable reference on androgenic disorders for professionals but not suitable for laypeople or medical students.
research Estrogens and the hair follicle. Ostrogene und der Haarfollikel
Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.
research The Hirsute Woman: Challenges in Evaluation and Management
Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.
research Pharmacologic Treatment of Polycystic Ovary Syndrome
The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.
research Gonadal Sex Steroids: Production, Action and Interactions in Mammals
The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
research The rationale for physiological testosterone replacement in women
Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.
research Spironolactone in dermatology: uses in acne and beyond
Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.