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SRD5A1 is crucial in advanced prostate cancer, and blocking both SRD5A1 and SRD5A2 is more effective than targeting SRD5A2 alone.

The over-the-counter supplement DHEA could make COVID-19 worse, especially in diabetics and people with G6PD deficiency.

Androgen deprivation therapy might be better for preventing COVID-19 than treating it.

Finasteride helps female-pattern hair loss.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

Sex-determining genes may affect male baldness.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Androgens can both increase and decrease hair growth in different parts of the body.

Finasteride may improve prostate cancer treatment outcomes.

Dutasteride and finasteride affect different cell types differently.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Testosterone may slow down wound healing and increase inflammation.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Men are more affected by COVID-19 due to differences in immune responses and protein expression.

Male hormones worsen kidney transplant damage, but blocking them helps.

Androgen receptor inactivation delays skin cancer onset and reduces incidence in mice, with gender differences in susceptibility.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.

A specific genetic mutation may increase male pattern baldness risk, especially in Europeans.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.

Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.

Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.