February 2017 in “Clinical dermatology open access journal” Men with early hair loss may have higher insulin resistance and should be checked for related health issues.
January 2008 in “Journal of The American Academy of Dermatology” ROS may affect hair loss related to hormones.
45 citations
,
August 2005 in “Bioorganic & medicinal chemistry” New compounds with carborane showed anti-androgen effects similar to flutamide.
May 2015 in “Endocrinología y nutrición” The conclusion is that adult males with muscle weakness and hormonal imbalances should be tested for Kennedy's disease.
48 citations
,
February 2008 in “Nutrition in Clinical Practice” Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.
25 citations
,
June 2019 in “Endocrine Related Cancer” Mutations in certain receptors can cause diseases and offer new treatment options.
6 citations
,
August 2018 in “BMJ open sport and exercise medicine” Resistance training might help with PCOS symptoms, but more research is needed.
195 citations
,
June 2005 in “American Journal of Human Genetics” Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.
123 citations
,
May 2020 in “Drug Development Research” Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.
119 citations
,
November 2009 in “Human Reproduction” Women with PCOS and higher androgen levels are more likely to have fatty liver disease.
100 citations
,
June 2002 in “Diabetologia” Parents of women with PCOS have a higher risk of Type II diabetes and insulin resistance, especially fathers.
67 citations
,
July 2006 in “Clinics in Dermatology” Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.
59 citations
,
April 2016 in “Breast Cancer Research and Treatment” Targeting vitamin D and androgen receptors may effectively treat triple-negative breast cancer, especially with chemotherapy.
50 citations
,
December 2008 in “Clinical Endocrinology” Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.
46 citations
,
June 2015 in “Fertility and Sterility” Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.
42 citations
,
January 2011 in “European Journal of Dermatology” Early balding men may have insulin resistance, but lifestyle changes can help.
35 citations
,
March 2011 in “International Journal of Dermatology” No true link between AGA and insulin resistance, but coexistence may worsen AGA.
34 citations
,
January 2014 in “Indian Dermatology Online Journal” Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.
21 citations
,
July 2019 in “Cardiovascular Research” High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.
21 citations
,
March 2019 in “Critical Reviews in Clinical Laboratory Sciences” The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
20 citations
,
May 2011 in “Cancer Biology & Therapy” Finasteride may improve prostate cancer treatment outcomes.
18 citations
,
May 2017 in “Fertility Research and Practice” Larger ovarian size is linked to higher insulin resistance in women with PCOS.
14 citations
,
September 2015 in “Expert Opinion on Therapeutic Targets” The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
12 citations
,
June 2013 in “The Prostate” Dutasteride and finasteride affect different cell types differently.
12 citations
,
March 2013 in “Gynecological Endocrinology” The study found a significant link between the renin-angiotensin system and insulin resistance in women with polycystic ovary syndrome.
11 citations
,
July 2016 in “Endocrinology” Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.
9 citations
,
September 2009 in “The Prostate” Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.
8 citations
,
November 2012 in “Journal of Endocrinological Investigation” Greek women with classic PCOS are more likely to have metabolic syndrome and insulin resistance than those with newer PCOS types.
8 citations
,
January 2003 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Women with myotonic dystrophy might get diseases related to male hormones because their body tissues are extra sensitive to these hormones.
7 citations
,
December 2014 in “Australasian journal of dermatology” Insulin resistance is not more common in idiopathic hirsutism patients than in healthy individuals.