research The Basic Science of Hair Biology
Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
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research Expression and function of nuclear receptor co-activator 4: evidence of a potential role independent of co-activator activity
NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
research 5α-Reductase Inhibitors Do Not Prevent the Development and Progression of Urothelial Cancer: In Vitro Evidence
5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.
research Hormones and the pilosebaceous unit
Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
research Female Pattern Hair Loss: a clinical and pathophysiological review
Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.
research The Postnatal Offspring of Finasteride-Treated Male Rats Shows Hyperglycaemia, Elevated Hepatic Glycogen Storage and Altered GLUT2, IR, and AR Expression in the Liver
Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.
research Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline
The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.
research Polycystic ovary syndrome
PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.
research Nonalcoholic fatty liver disease and polycystic ovary syndrome
People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.
research Principles of Hair Cycle Control
Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.
research No evidence for the immunocompetence handicap hypothesis in male humans
Higher free testosterone levels in men are linked to a stronger immune response, not weaker.
research MENSTRUAL DISORDERS IN ADOLESCENTS
The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
research Perspectives of Kennedy's disease
Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
research Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor β2 Expression
Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
research Ovarian Hypertension: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.
research Sex Hormone-Binding Globulin (SHBG) as an Early Biomarker and Therapeutic Target in Polycystic Ovary Syndrome
SHBG may be a useful early indicator and treatment target for PCOS.
research Evidence for Masculinization of Adipokine Gene Expression in Visceral and Subcutaneous Adipose Tissue of Obese Women With Polycystic Ovary Syndrome (PCOS)
Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.
research Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells
High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
research Matriptase activation and shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells
Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
research The biology of hair diversity
Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.
research Steroid plant hormones: Effects outside plant kingdom
Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
research Alternative treatment of polycystic ovary syndrome: pre-clinical and clinical basis for using plant-based drugs
Plant-based drugs are effective and safe alternatives for managing PCOS symptoms.
research Studying the genetic predisposing factors in the pathogenesis of acne vulgaris
Genetics play a role in acne, but how exactly they contribute is not fully understood.
research Genome-wide association study of skin complex diseases
Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.
research Advances in male hormone substitution therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research Clinicopathologic study of 90 cases of trichofolliculoma
Trichofolliculoma is a unique benign tumor mainly affecting middle-aged adults' faces, often misdiagnosed without histopathology.
research Adipocyte-myofibroblast transition as a possible pathophysiological step in androgenetic alopecia
AMT may cause hair loss and changing dWAT activity could help treat it.
research Comprehensive Transcriptome Profiling of Balding and Non-Balding Scalps in Trichorhinophalangeal Syndrome Type I Patient
The study found genetic differences related to hair development that may explain hair loss in a patient with Trichorhinophalangeal syndrome type I.
research Testosterone Treatment in Women – An Overview
Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.
research Shedding light on therapeutics in alopecia and their relevance to COVID-19
Some alopecia treatments might help treat COVID-19, but more research is needed.