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Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

PM-9 and finasteride effectively inhibit the enzyme that converts testosterone to DHT.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

The method effectively measures drug impact on DHT levels in prostate treatments.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

New treatments for excessive hair growth in women include insulin modulators and enzyme inhibitors.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Gut microbes significantly affect brain steroid levels.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

Certain gene variants are linked to severe acne, especially in males.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Finasteride may cause kidney damage.

Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.