24 citations
,
March 2001 in “Journal of Endocrinology/Journal of endocrinology” Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.
16 citations
,
October 2007 in “Andrologia” DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
3 citations
,
April 2015 in “American journal of biomedical sciences” Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.
165 citations
,
December 2002 in “Molecular and Cellular Endocrinology” Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
251 citations
,
October 2014 in “The Journal of Clinical Endocrinology & Metabolism” The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
123 citations
,
May 2020 in “Drug Development Research” Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.
May 2015 in “Endocrinología y nutrición” The conclusion is that adult males with muscle weakness and hormonal imbalances should be tested for Kennedy's disease.
1540 citations
,
October 2008 in “Fertility and Sterility” The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
282 citations
,
October 2006 in “The Journal of Clinical Endocrinology and Metabolism” The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
233 citations
,
November 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
227 citations
,
January 1998 in “Journal of Endocrinology” Cells from balding scalps have more androgen receptors than cells from non-balding scalps.
204 citations
,
February 2000 in “Current Medicinal Chemistry” Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
196 citations
,
May 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Sebocytes play a key role in controlling androgen levels in human skin.
186 citations
,
July 1998 in “Journal of Cutaneous Medicine and Surgery” Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.
114 citations
,
March 2018 in “PLOS Medicine” Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.
70 citations
,
January 2009 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Androgens slow hair growth by altering Wnt signaling in balding cells.
54 citations
,
February 1993 in “Endocrine reviews” Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.
41 citations
,
November 2003 in “Annals of the New York Academy of Sciences” Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.
39 citations
,
March 2018 in “Archives of Dermatological Research” Androgens may block hair growth signals, targeting this could treat hair loss.
26 citations
,
January 1994 in “Hormone and Metabolic Research” Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.
25 citations
,
November 2001 in “Kidney International” Male hormones worsen kidney transplant damage, but blocking them helps.
12 citations
,
September 2017 in “Molecular and Cellular Endocrinology” Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.
8 citations
,
March 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.
6 citations
,
September 2005 in “Expert Opinion on Pharmacotherapy” Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
6 citations
,
January 1996 in “Endocrine-related Cancer” Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.
December 2023 in “Frontiers in endocrinology” Excess androgens may cause PCOS, not just be a symptom.
25 citations
,
June 2019 in “Endocrine Related Cancer” Mutations in certain receptors can cause diseases and offer new treatment options.
27 citations
,
February 2014 in “Planta Medica” Scutellaria baicalensis extract and baicalin may help prevent hair loss.
209 citations
,
September 2008 in “Dermatologic Therapy” Androgens can both increase and decrease hair growth in different parts of the body.
123 citations
,
December 2015 in “Journal of Neuroendocrinology” New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.