66 citations
,
January 2001 in “Vitamins and hormones” Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
66 citations
,
June 2013 in “Journal of Dermatological Treatment” Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.
66 citations
,
February 2009 in “British Journal of Dermatology” Chinese men have lower AGA rates than Caucasians, with type III vertex most common; family history is important.
66 citations
,
June 2006 in “Journal of The American Academy of Dermatology” Finasteride increases hair weight and count in men with hair loss, with best results after four years.
66 citations
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April 2002 in “Journal of The American Academy of Dermatology” Finasteride increases hair weight and count in men with hair loss.
65 citations
,
April 2018 in “Oncotarget” Anabolic androgenic steroids can increase cancer risk and disrupt hormones.
65 citations
,
April 2002 in “Journal of Alternative and Complementary Medicine” Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.
65 citations
,
October 1999 in “Journal of The American Academy of Dermatology” Finasteride effectively reduces hair loss by decreasing androgen levels.
65 citations
,
April 2020 in “International Journal of Molecular Sciences” PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.
64 citations
,
August 2019 in “Circulation” ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.
64 citations
,
March 1984 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.
64 citations
,
March 2017 in “Journal of Cosmetic Dermatology” PRP treatment may increase hair density and reduce hair loss, but more research is needed.
64 citations
,
January 2005 in “International Journal of Dermatology” Hair transplant destroyed by lichen planopilaris.
63 citations
,
April 2017 in “Acta psychiatrica Scandinavica” Higher prenatal and adult androgen levels are linked to alcohol dependence and withdrawal severity.
63 citations
,
August 2022 in “Diagnostics” Hirsutism can occur in women with PCOS even if their androgen levels are normal, making diagnosis challenging.
63 citations
,
August 2008 in “Journal of Cosmetic Dermatology” Cuscuta reflexa extract may help treat hair loss caused by hormones.
63 citations
,
November 1999 in “British journal of dermatology/British journal of dermatology, Supplement” Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
63 citations
,
October 2005 in “Archives of Dermatology” Shorter, thinner hairs indicate AGA, while longer, thicker hairs suggest CTE; counting and measuring shed hairs helps diagnose hair loss type.
62 citations
,
August 2018 in “Frontiers in Endocrinology” Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
62 citations
,
March 2008 in “American Journal of Human Genetics” Hair loss gene found on chromosome 3q26.
62 citations
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January 2003 in “Dermatology” Sunlight worsens hair loss; protect scalp.
61 citations
,
September 2016 in “Journal of Cosmetic and Laser Therapy” Platelet-rich plasma (PRP) was found not effective in treating male-patterned hair loss.
60 citations
,
January 2007 in “Human Genetics” AR polyglycine repeat doesn't cause baldness.
60 citations
,
September 2016 in “Dermatologic Surgery” PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.
59 citations
,
April 2016 in “Breast Cancer Research and Treatment” Targeting vitamin D and androgen receptors may effectively treat triple-negative breast cancer, especially with chemotherapy.
59 citations
,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
59 citations
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August 2004 in “Human Reproduction Update” Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.
59 citations
,
January 1976 in “Vitamins and hormones” Prostate cells have proteins that bind to specific hormones, which can increase protein production when activated by these hormones.
58 citations
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January 2003 in “Thrombosis and Haemostasis” Testosterone may slow down wound healing and increase inflammation.
58 citations
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June 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.