January 2023 in “Austin Journal of Obstetrics and Gynecology” PCOS affects many young women in KSA, with mild cases being most common.
December 2022 in “International journal of preventive, curative & community medicine” PCOS is a common hormonal disorder in women, causing symptoms like acne and irregular periods, and is managed with medication and lifestyle changes.
December 2022 in “Jurnal Kesehatan Jompa” AAG causes hair loss in many people, with limited treatments like finasteride, minoxidil, light therapy, and hair transplants.
July 2018 in “Elsevier eBooks” Some drugs can cause reversible hair loss, but certain chemotherapy drugs may lead to permanent hair loss; drugs can also change hair color and texture.
Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.
October 2022 in “Biomedicines” Finasteride in male rats causes liver and metabolic issues in their offspring.
January 2003 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” Testosterone therapy can improve skin and hair in men with low testosterone but may cause skin irritation with certain treatments.
37 citations
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February 2023 in “Gut Microbes” Gut bacteria can lower androgen levels in male mice.
April 2019 in “Journal of the Endocrine Society” A 31-year-old woman was diagnosed with Complete Androgen Insensitivity Syndrome much later than usual, leading to a call for earlier detection and treatment guidelines.
224 citations
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February 2013 in “The Journal of clinical investigation/The journal of clinical investigation” ERG increases SOX9, promoting prostate cancer growth and invasion.
120 citations
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April 2019 in “The Journal of clinical investigation/The journal of clinical investigation” Both estrogens and androgens are important for health in both males and females.
101 citations
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April 1994 in “Baillière's clinical endocrinology and metabolism” 5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
97 citations
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April 2016 in “Andrology” Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.
97 citations
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November 1986 in “Journal of Steroid Biochemistry” Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
63 citations
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December 2013 in “PLoS ONE” Finasteride may reduce prostate cancer spread by lowering certain enzyme levels.
48 citations
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June 2014 in “Neurobiology of Disease” The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.
42 citations
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September 2007 in “The Journal of Clinical Endocrinology and Metabolism” The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.
36 citations
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October 2009 in “Journal of biological chemistry/The Journal of biological chemistry” Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
29 citations
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February 2018 in “Genetics research international” Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.
14 citations
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May 2012 in “Endocrine Research” The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.
8 citations
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June 2019 in “Scientific Reports” Increased PPARGC1α relates to hair thinning in common baldness.
7 citations
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January 2020 in “Frontiers in Pharmacology” Jagged1 and Epidermal Growth Factor together significantly increased hair growth in mice with androgen-suppressed hair.
2 citations
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January 2025 in “Pharmaceutical Research” Angelica gigas Nakai root extracts may help with cancer, pain, memory loss, and metabolic issues.
research Acne
2 citations
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May 2011 in “Harper's Textbook of Pediatric Dermatology” Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.
1 citations
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August 2023 in “Curēus” Metformin helps reduce PCOS-related infertility by improving insulin sensitivity and inducing ovulation.
1 citations
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January 2022 in “BMC Genomic Data” The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.
1 citations
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February 2014 in “Archiv Der Pharmazie” Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.
January 2026 in “Scientific Reports” Sesamin may help treat hair loss by affecting specific cell pathways.
September 2011 in “American Journal of Clinical Dermatology” The birth control pill containing ethinylestradiol and chlormadinone may help treat acne and other skin and hair conditions related to hormones.
January 2023 in “Iranian Journal of Pharmaceutical Research” Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.