18 citations
,
May 2017 in “Experimental Dermatology” AMT may cause hair loss and changing dWAT activity could help treat it.
3 citations
,
March 2014 in “Turkderm” Hair loss in men can be slowed or reversed with treatments like minoxidil and finasteride, but it resumes if treatment stops. It may also indicate early heart disease and obesity.
August 2025 in “Fabad Journal of Pharmaceutical Sciences” Bicalutamide effectively treats prostate cancer but needs careful monitoring for side effects.
200 citations
,
October 2009 in “European journal of endocrinology” Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.
100 citations
,
July 2004 in “The Journal of Sexual Medicine” Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.
56 citations
,
January 2015 in “Circulation” Finasteride helps reduce heart issues and improves heart function.
9 citations
,
January 2018 in “Journal of the European Academy of Dermatology and Venereology” A male patient developed frontal fibrosing alopecia after antiandrogen therapy for prostate cancer.
9 citations
,
January 2017 in “Annals of Dermatology” The study found genetic differences related to hair development that may explain hair loss in a patient with Trichorhinophalangeal syndrome type I.
August 2025 in “Therapeutics” Low-dose DMSO may help treat castration-resistant prostate cancer by reducing key cancer cell receptors.
September 2025 in “Deleted Journal” Blocking androgen receptors boosts macrophages' ability to clear certain bacteria.
January 2019 in “OpenBU/Boston University Institutional Repository (Boston University)” Women with PCOS often show signs of excess androgens like hirsutism, acne, and alopecia, with variations across ethnic groups.
159 citations
,
July 2006 in “Endocrine Reviews” Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
59 citations
,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
44 citations
,
March 2012 in “Fitoterapia” Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.
38 citations
,
October 1988 in “Clinics in Dermatology” Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.
30 citations
,
September 2017 in “Clinics in Dermatology” Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.
23 citations
,
August 2005 in “Expert opinion on pharmacotherapy” New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
18 citations
,
July 2020 in “Basic and Clinical Andrology” Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.
8 citations
,
January 2020 in “Plastic and Aesthetic Nursing” The article concludes that different types of hair loss require specific treatments and psychological support is important.
6 citations
,
July 2017 in “Case Reports” Hair loss, known as androgenic alopecia, can start in teenage years and may not always be hormone-related. It's important to do extra tests in young cases and remember it can greatly affect a teenager's mental health.
5 citations
,
December 2018 in “Frontiers in Endocrinology” Differences in androgen receptor expression and tissue properties may lead to higher cryptorchidism risk in certain rats.
4 citations
,
November 2022 in “Frontiers in endocrinology” The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.
1 citations
,
January 2006 Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.
April 2010 in “The Journal of Urology” Human prostate cells produce more WISP1/CCN4 when there's not enough oxygen.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
143 citations
,
August 1991 in “Endocrinology” Androgens, like testosterone, are crucial for early testicular descent in rats.
35 citations
,
October 2011 in “Medicine and science in sports and exercise” Muscles can make their own androgens, which may help muscle growth.
22 citations
,
October 2001 in “Biochemical Pharmacology” GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
19 citations
,
July 2019 in “Journal of Endocrinology” GTx-024 and Danazol affect the uterus like DHT, while GTx-007 has little impact.
17 citations
,
December 2004 in “The Journal of Men's Health & Gender” Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.