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Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

The method accurately measures certain steroids in human hair, showing different levels in males and females.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Mouse genital development depends on male or female hormones for specific features.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

Androgens prevent hair growth by changing Wnt signals in cells.

Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.

The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.

Androgens and estrogens are crucial for male reproductive health, affecting hormone levels and tissue function.

Estrogens can reduce DHT production in hair follicles, but are less effective than finasteride and progesterone.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

CAG repeat polymorphism and prostate zone volume are not reliable markers of long-term androgen sensitivity.

A point mutation in the androgen receptor gene causes complete androgen insensitivity.

L-threonate may help prevent balding by blocking a key protein.

Androgens like testosterone increase colon muscle contractions by affecting calcium pathways.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Human keratinocytes do not naturally respond to androgens.

Many acne patients have high androgen levels, which may lead to PCOD, but treatments like oral contraceptives and antiandrogens can help.

Androgens don't directly affect hair cell growth or protein production.

Treatment during development affects hormone balance and sexual behavior in male rats.

Finasteride changes androgen receptor location in rat epididymis without altering tissue structure.

Male hormones worsen kidney transplant damage, but blocking them helps.

Androgens affect skin conditions like acne and hair loss through specific biochemical pathways.

Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.

DHT stops hair regrowth in mice, similar to human hair loss.