research Study of serum vitamin D levels in men with premature androgenetic alopecia
Men with early hair loss have lower vitamin D levels.
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research Development of fluridil, a topical suppressor of the androgen receptor in androgenetic alopecia
Fluridil promotes hair growth safely and effectively for androgenetic alopecia.
research Anti-Androgen Treatment of Hirsute Women: A Study on Stress Responses
The treatment reduced hair growth and testosterone in women with excess hair and had some effects on stress responses.
research Absence of chemotherapy-induced alopecia with paclitaxel in a case of hypothyroidism: case report
A woman with low thyroid function did not lose her hair during chemotherapy, possibly because her hair follicles were less affected by the treatment.
research Evaluation of serum G protein-coupled estrogen receptor 1 (GPER-1) levels in patients with androgenetic alopecia
Alopecia patients have less GPER-1, which might affect hair loss.
research Lisinopril-Induced Alopecia: A Case Report
Lisinopril, a heart medication, probably caused hair loss in a patient, which stopped after switching drugs.
research Regulatory roles of androgens in cutaneous wound healing
Testosterone may slow down wound healing and increase inflammation.
research Recent discoveries and developments of androgen receptor based therapy for prostate cancer
New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
research Improving selective androgen receptor modulator discovery and preclinical evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
research Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression (Catagen) by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla
All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
research Hirsutism and the Variable Response of the Pilosebaceous Unit to Androgen
Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.
research The Role of Androgens in Health and Disease in Females: A Narratıve Review
Androgens affect many aspects of female health, and more research is needed to understand their roles and treatment potential.
research Evaluation of Serum Levels of Nesfatin-1 and Insulin resistance in Patients with Acne Vulgaris
Insulin resistance and nesfatin-1 are linked to acne severity.
research Regulation of masculinization: androgen signalling for external genitalia development
Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
research Molecular basis of androgenetic alopecia: From androgen to paracrine mediators through dermal papilla
Male pattern baldness involves hormones and cell signals affecting hair growth.
research Androgen Deprivation Therapy in Prostate Cancer: Focusing on Sexual Side Effects
Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.
research Ganoderma lucidum is an inhibitor of testosterone-induced prostatic hyperplasia in rats
Ganoderma lucidum may help treat enlarged prostate in rats.
research Androgen receptor: A promising therapeutic target in breast cancer
The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
research Prolongation of off-cycle interval by finasteride is not associated with survival improvement in intermittent androgen deprivation therapy in LNCaP tumor model
Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.
research Unravelling the link between insulin resistance and androgen excess
AKR1C3 could be a treatment target for metabolic issues in PCOS.
research Relative Prevalence of Different Androgen Excess Disorders in 950 Women Referred because of Clinical Hyperandrogenism
Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.
research Anti-androgens for the treatment of hirsutism
Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.
research Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells
PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.
research Hair follicle stem cell differentiation is inhibited through cross‐talk between Wnt/β‐catenin and androgen signalling in dermal papilla cells from patients with androgenetic alopecia
Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.
research Additive in vivo growth-inhibitory effects of flutamide and finasteride on androgen-sensitive Shionogi 115 carcinoma
Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.
research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors
Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.
research A phase IIA randomized, placebo-controlled clinical trial to study the efficacy and safety of the selective androgen receptor modulator (SARM), MK-0773 in female participants with sarcopenia
MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.
research Increased androgen bioavailability is associated with non-alcoholic fatty liver disease in women with polycystic ovary syndrome
Women with PCOS and higher androgen levels are more likely to have fatty liver disease.
research The therapeutic use of androgens in women
Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
research Tamoxifen for flutamide/finasteride-induced gynecomastia
Tamoxifen effectively treats gynecomastia without causing impotence.