research Screening of Anti-Hair Loss Plant Raw Materials Based on Reverse Network Pharmacology and Experimental Validation
Certain plant extracts may help prevent hair loss and promote hair growth safely.
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research Signal integrator function of CXXC5 in Cancer
CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
research Hair Growth Promoting Effects of Solubilized Sturgeon Oil and Its Correlation with the Gut Microbiome
Oral sturgeon oil promotes hair growth and improves gut health.
research Hair matrix germinative epidermal cells confer follicle-inducing capabilities on dermal sheath and high passage papilla cells
Hair growth can be stimulated by combining certain skin cells, which can rejuvenate old cells and cause them to specialize in hair follicle creation.
research Insulin resistance as risk factor for the development of type 2 diabetes mellitus: a systematic approach
Insulin resistance increases the risk of developing type 2 diabetes and other health issues.
research Invasion and increased expression of S100A4 and CYR61 in mesenchymal transformed breast cancer cells is downregulated by GnRH
GnRH treatment can reduce breast cancer cell invasion.
research Phenytoin‐mediated androgen metabolism in gingival fibroblasts
Levamisole and finasteride can reduce DHT production, potentially preventing phenytoin-induced gum overgrowth.
research Androgen receptor–mediated inhibition of cutaneous wound healing
Blocking testosterone speeds up wound healing in males.
research Androgen receptor–mediated inhibition of cutaneous wound healing
Lowering testosterone speeds up wound healing in male mice.
research Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells
PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.
research Androgen Receptor–Mediated Paracrine Signaling Induces Regression of Blood Vessels in the Dermal Papilla in Androgenetic Alopecia
Male pattern baldness is linked to higher levels of a certain receptor in the scalp, which leads to the shrinking of blood vessels and hair loss. Early treatment targeting this receptor could be more effective.
research Androgen receptor-mediated gene activation in prostate cancer cells
Androgen receptors help prostate cancer cells grow and resist drugs.
research ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer
ERG increases SOX9, promoting prostate cancer growth and invasion.
research Membrane androgen receptors may mediate androgen reinforcement
Androgen self-administration might be controlled by membrane receptors, not nuclear ones.
research Androgen‐induced neurite outgrowth is mediated by neuritin in motor neurones
Androgens help motor neurons grow by increasing neuritin.
research 0885 The androgen-THY1 axis mediates sexual dimorphism in dermal adipogenesis and fibrosis
Androgens reduce THY1 in skin cells, leading to less fat, more fibrosis, and worse healing in males.
research Sex Differences in Opioid-Mediated Effects: Role of Androgens
Men and women react differently to opioids, with hormones potentially influencing these differences.
research Androgen Induction of Follicular Epithelial Cell Growth Is Mediated via Insulin-like Growth Factor-I from Dermal Papilla Cells
Male hormones promote hair cell growth by using a growth factor from nearby skin cells.
research Contribution of androgens to chronic allograft nephropathy is mediated by dihydrotestosterone
Male hormones worsen kidney transplant damage, but blocking them helps.
research Suppression of FOXO1 activity by SIRT1-mediated deacetylation weakening the intratumoral androgen autocrine function in glioblastoma
Targeting Sirt1 can reduce androgen levels and slow glioblastoma growth.
research Androgens in female pig reproduction: actions mediated by the androgen receptor
Androgens may improve pig reproduction by enhancing ovulation and litter size.
research Induction of transforming growth factor-beta 1 by androgen is mediated by reactive oxygen species in hair follicle dermal papilla cells
Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.
research Maternal androgen excess inhibits fetal cardiomyocytes proliferation through RB-mediated cell cycle arrest and induces cardiac hypertrophy in adulthood
Excess maternal androgens can cause heart problems in offspring.
research THERAPEUTIC HOTLINE: Genetic variations in the androgen receptor gene and finasteride response in women with androgenetic alopecia mediated by epigenetics
Women with greater androgen sensitivity respond better to finasteride for hair loss.
research Androgens in women
Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.
research Androgens in women
Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.
research Polymorphisms in androgen and estrogen receptor genes: effects on male aging
Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.
research Probing androgen receptor co-factor selectivity profiles: a chemical tool to determine cross-talk between androgen receptor and β-catenin in vivo
PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
research Control of androgen receptor expression in human keratinocytes and in a reconstituted human epidermis model with selective antisense oligonucleotides
Antisense oligonucleotides can reduce androgen receptor levels in skin cells, suggesting potential for treating skin disorders.
research Abstract 5561: 20(S)-Protopanaxadiol-aglycone downregulates full-length and ligand-independent splice variants of androgen receptor
20(S)-Protopanaxadiol-aglycone may help prevent and treat prostate cancer by reducing androgen receptor activity.