research COVID-19 Severity and Androgen Receptor Polymorphism
Men with more CAG repeats in the androgen receptor gene and lower testosterone levels may experience more severe COVID-19.
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research Insights into Male Androgenetic Alopecia: Differential Gene Expression Profiling of Plucked Hair Follicles and Integration with Genetic Data
Gene differences found in hair follicles linked to male baldness.
research Association between male pattern baldness and prostate disease: A meta-analysis
Men with male pattern baldness have a higher risk of aggressive prostate cancer and benign prostatic hyperplasia.
research Steroid Hormones
Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
research Purple corn extract improves benign prostatic hyperplasia by inhibiting 5 alpha-reductase type 2 and inflammation in testosterone propionate-induced rats
Purple corn extract may help reduce prostate enlargement and inflammation.
research Dexamethasone, a Synthetic Glucocorticoid, Induces the Activity of Androgen Receptor in Human Dermal Papilla Cells
Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.
research Letter to the Editor on “COVID-19 Infection in Men on Testosterone Replacement Therapy”
The letter suggests testosterone replacement therapy might worsen COVID-19 outcomes.
research 4th Intercontinental Meeting of Hair Research Societies 2004 The "World of Hair"
The meeting presented new findings on hair stem cells, pigmentation, genetics, and modern hair treatment techniques.
research Double Knockdown of the Androgen Receptor Target Genes DKK1 and SFRP1 Does Not Potentiate the Hair Growth-Promoting Effect of SFRP1 Silencing in Healthy Human Hair Follicles Ex Vivo
Silencing SFRP1 alone promotes hair growth, but adding DKK1 does not help.
research 24-Hydroxycholesterol suppresses steroid 5α-reductase-catalyzed conversion in human glioblastoma cell lines: A novel link between brain cholesterol homeostasis and androgen metabolism
24-Hydroxycholesterol reduces DHT formation in brain cancer cells, linking cholesterol and hormone metabolism.
research DERMATOLOGICAL CONDITIONS IN TRANSGENDER PATIENTS: A SYSTEMATIC REVIEW
Transgender individuals face unique skin issues, often due to hormone therapy, requiring specialized and stigma-free dermatologic care.
research Cross-kingdom delivery and putative gene modulation of androgen pathways by plant-derived exosome-like nanoparticles from polygoni multiflori radix promotes hair growth via miRNA cargo
Plant-derived nanoparticles from Polygoni Multiflori Radix promote hair growth better than Minoxidil by affecting androgen pathways.
research Low-Dose Dimethyl Sulfoxide (DMSO) Suppresses Androgen Receptor (AR) and Its Splice Variant AR-V7 in Castration-Resistant Prostate Cancer (CRPC) Cells
Low-dose DMSO may help treat castration-resistant prostate cancer by reducing key cancer cell receptors.
research Microneedle-mediated hypoxic extracellular vesicle-encapsulated selenium nanoparticles delivery to treat androgenetic alopecia
The new treatment using microneedle patches shows promise for better hair growth in androgenetic alopecia.
research The Glucocorticoid Resistance Syndrome. Two Cases of a Novel Pathogenic Variant in the Glucocorticoid Receptor Gene
A new gene variant causes glucocorticoid resistance in a mother and son.
research Synthesis and application of clinically approved small-molecule drugs targeting androgen receptor
Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.
research Androgen-induced norepinephrine release in male accessory sex organ smooth muscle growth and differentiation
Androgens increase norepinephrine release, promoting smooth muscle growth in male sex organs, which may contribute to benign prostatic hypertrophy.
research Acne-Associated Syndromes
Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
research Pharmacological Control of Reproduction in the Dog and Cat
Different drugs are used to manage breeding, prevent or end pregnancy, and treat reproductive issues in dogs and cats.
research Diffuser Haarausfall und klinische Endokrinologie: Neue Erkenntnisse
Hormones significantly affect hair growth and loss, with potential for new treatments.
research Eziopatogenesi e terapia dell'acne:studio epidemiologico delle caratteristiche cliniche di una popolazione di pazienti affetti da acne e analisi dei polimorfismi del gene codificante per il recettore degli androgeni e del gene codificante per il citocromo P-450 1A1
Hereditary factors affect acne duration, not severity, and late-onset acne in females has different causes.
research In That Issue: Proceedings From the Third Intercontinental Meeting of Hair Research Societies
The meeting covered advances in understanding hair growth, causes of hair loss, and potential treatments.
research The effects of extra cellular matrix and growth factors on dermal papilla cell proliferation
Different substances affect hair and skin cell growth in various ways.
research Studies of the modulation of MHC antigen and cell adhesion molecule expression on human dermal papilla cells
Different substances affect hair and skin cell growth in various ways, with some promoting and others inhibiting cell proliferation.
research Dyslipidemia in patients with androgenetic alopecia. Statins, finasteride or both?
Alopecia patients have higher heart disease risk; statins and finasteride may help.
research Early-onset androgenetic alopecia and endocrine disruptors
Endocrine disruptors may cause early hair loss.
research Early androgenetic alopecia as a marker of insulin resistance
Early hair loss may indicate risk of insulin resistance.
research Evidence for Masculinization of Adipokine Gene Expression in Visceral and Subcutaneous Adipose Tissue of Obese Women With Polycystic Ovary Syndrome (PCOS)
Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.
research COVID-19 pandemic: what about the gonads?
COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.
![Synthesis, Biological Evaluation, and Molecular Docking of 4-Amino-2H-benzo[h]chromen-2-one Analogs Containing the Piperazine Moiety](/images/research/2ecf4eed-7dbe-4f1a-83db-739625546cdd/small/31808.jpg)
research Synthesis, biological evaluation and molecular docking of 4-Amino-2H-benzo[h]chromen-2-one (ABO) analogs containing the piperazine moiety
Analog 23 is a promising compound for prostate cancer treatment.