343 citations
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December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
234 citations
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December 1996 in “Journal of The American Academy of Dermatology” Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.
162 citations
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August 2002 in “Survey of Ophthalmology” Latanoprost can make eyelashes longer, thicker, and darker.
156 citations
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October 1996 in “Science of The Total Environment” Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.
111 citations
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March 2012 in “Expert Opinion on Drug Delivery” Liposomes could improve how skin care products work but are costly and not very stable.
103 citations
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June 2007 in “Endocrinology and Metabolism Clinics of North America” Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.
81 citations
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June 2014 in “American Journal of Men's Health” Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.
63 citations
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April 2003 in “Journal of The European Academy of Dermatology and Venereology” Minoxidil use increases facial hair growth in females, more in older users.
57 citations
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December 2018 in “JAMA Surgery” Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.
57 citations
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October 2018 in “Journal of The American Academy of Dermatology” Platelet-rich plasma treatment can significantly increase hair count and density in men with pattern baldness, and these improvements can last up to 3 months.
55 citations
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March 2000 in “American journal of clinical dermatology” Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
53 citations
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October 2012 in “The FASEB Journal” Bimatoprost, a glaucoma medication, may also help treat hair loss.
49 citations
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August 2003 in “Journal of The American Academy of Dermatology” Higher IGF-1 levels in hair follicles link to better finasteride results for hair loss.
45 citations
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February 2005 in “Steroids” Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.
38 citations
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June 2015 in “Expert Opinion on Therapeutic Targets” Blocking the prolactin receptor might help treat various diseases, but more research is needed.
38 citations
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December 2011 in “British Journal of Dermatology” Menopause-related hormonal changes affect hair but are not the only cause of hair changes in middle-aged women.
36 citations
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May 2017 in “The journal of sexual medicine” Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.
33 citations
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January 2005 in “Dermatology” Trichoscan is a reliable method for measuring hair growth and monitoring treatment effectiveness in hair loss.
32 citations
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December 2013 in “Biological & Pharmaceutical Bulletin” Rice bran extract can potentially treat hair loss by promoting hair growth and increasing the number of hair follicles.
32 citations
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July 1999 in “Fertility and Sterility” Finasteride and flutamide both reduce hair growth, but finasteride has fewer side effects.
30 citations
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June 2015 in “British Journal of Dermatology” Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.
29 citations
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January 2007 in “Dermatologic Clinics” Photodynamic Therapy is an effective treatment for mild to severe acne.
25 citations
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May 2003 in “Expert Opinion on Therapeutic Patents” Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
24 citations
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July 1994 in “Molecular Endocrinology” Researchers found an RNA transcript that might help control a growth factor linked to tumor development.
22 citations
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June 2002 in “Seminars in cutaneous medicine and surgery” Laser hair removal works well for people with dark hair and light skin, but it's less effective for light hair or dark skin; improvements are expected.
18 citations
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April 2010 in “Journal of Chromatography B” New method measures finasteride in blood quickly and accurately.
16 citations
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November 2023 in “Scientific Reports” The niosomes effectively target hair follicles for acne treatment.
12 citations
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June 2016 in “Reviews in Endocrine and Metabolic Disorders” Some skin diseases and their treatments can negatively affect male fertility.
11 citations
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May 2023 in “Journal of Cancer Research and Clinical Oncology” CRISPR/Cas systems show promise for cancer treatment by targeting miRNAs, but delivery and specificity challenges remain.
10 citations
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February 2020 in “Endocrine” Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.