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research Ultrasound-activated particles as CRISPR/Cas9 delivery system for androgenic alopecia therapy

47 citations , December 2019 in “Biomaterials”

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

Androgens Modify Wnt Agonists/Antagonists Expression Balance in Dermal Papilla Cells Preventing Hair Follicle Stem Cell Differentiation in Androgenetic Alopecia

research Androgens modify Wnt agonists/antagonists expression balance in dermal papilla cells preventing hair follicle stem cell differentiation in androgenetic alopecia

47 citations , October 2016 in “Molecular and Cellular Endocrinology”

Androgens prevent hair growth by changing Wnt signals in cells.

research Different gene expression profile observed in dermal papilla cells related to androgenic alopecia by DNA macroarray analysis

47 citations , July 2004 in “Journal of Dermatological Science”

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia

research Differential Expression between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia

46 citations , April 2016 in “Journal of Investigative Dermatology”

New genes found linked to balding, may help develop future treatments.

Regulation of Masculinization: Androgen Signaling for External Genitalia Development

research Regulation of masculinization: androgen signalling for external genitalia development

45 citations , April 2018 in “Nature Reviews Urology”

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

research Androgen receptor gene polymorphism and polycystic ovary syndrome

45 citations , November 2012

The conclusion is that androgen receptor gene polymorphism might be a marker for polycystic ovary syndrome, but more research is needed.

An Observational Retrospective Evaluation of 79 Young Men with Long-Term Adverse Effects After Use of Finasteride Against Androgenetic Alopecia

research An observational retrospective evaluation of 79 young men with long-term adverse effects after use of finasteride against androgenetic alopecia

43 citations , January 2016 in “International Journal of Andrology”

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

research The investigation of insulin resistance and metabolic syndrome in male patients with early-onset androgenetic alopecia

42 citations , January 2011 in “European Journal of Dermatology”

Early balding men may have insulin resistance, but lifestyle changes can help.

research Autologous Micrografts from Scalp Tissue: Trichoscopic and Long-Term Clinical Evaluation in Male and Female Androgenetic Alopecia

41 citations , January 2020 in “BioMed Research International”

Micrografts improve hair density and thickness without side effects.

research Low-level laser therapy for the treatment of androgenic alopecia: a review

41 citations , December 2017 in “Lasers in Medical Science”

Low-Level Laser Therapy (LLLT) is a safe and effective treatment for common hair loss, but more research is needed to find the best power and wavelength for treatment.

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