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The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Hair loss is caused by genetics and hormones, diagnosed through examination and biopsy, and treated with medications or surgery.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Spironolactone most effective for hirsutism, but has side effects.

2% topical minoxidil effectively treats female hair loss with minimal side effects.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.

Minoxidil helps hair growth and reduces shedding in women.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Hormone therapy for excessive hair growth is as good with GnRHa as with high-dose CPA, but GnRHa has longer-lasting results.