research Association of oxidative stress in mild patchy alopecia areata: a case- control study
Oxidative stress is linked to mild patchy alopecia areata.
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research Histopathological Analysis on keratin2-6 g Expression in Hair Mutant Mouse Hague
Keratin2-6g is crucial for hair follicle development, with mutations causing cell degeneration and vacuolation.
research Present Chemotherapy Induced Alopecia and Research in Future
Current treatments for hair loss from chemotherapy are limited, but new methods are being researched.
research JAK1 gain-of-function variant causes alopecia areata, atopic dermatitis, and autoimmune thyroid disease
A JAK1 variant causes hair loss, skin issues, and thyroid disease, but treatment with a specific inhibitor can help.
research Highlights from the Literature
Apoptosis, not oxidative stress, is linked to aging in mice with mtDNA mutations.
research Expansion of specialized epidermis induced by hormonal state and mechanical strain
Nipple area expansion in mice needs both pregnancy hormones and mechanical strain.
research Disturbed Keratinocyte Differentiation in Transgenic Mice and Organotypic Keratinocyte Cultures as a Result of Spermidine/Spermine N1-Acetyltransferase Overexpression
Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.
research Stress-sensing in the human greying hair follicle: Ataxia Telangiectasia Mutated (ATM) depletion in hair bulb melanocytes in canities-prone scalp
Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
research Поняття міжкультурної комунікації та порівняльна характеристика німецької та української культур (на матеріалі німецької мови)
Low-dose effects in rodent studies are hard to confirm due to confounding factors and control group variability.
research Transcription Regulation and Protein Subcellular Localization of the Truncated Basic Hair Keratin hHb1-ΔN in Human Breast Cancer Cells
A truncated protein linked to breast cancer may change cell adhesion.
research Coarse to Fine Hair Conversion Induced by Zinc in C57/6J Mice.
Zinc made mice's coarse hair turn into fine hair without affecting skin structure.
research 197 A novel splice site mutation in LIPH identified in a Japanese patient with autosomal recessive woolly hair
Researchers found a new genetic mutation linked to a hair condition in a Japanese boy.
research Differential distribution of the epigenetic marker 5‐hydroxymethylcytosine occurs in hair follicle stem cells during bulge activation
The marker 5-hmC changes in hair follicle stem cells when they start to grow.
research Aryl hydrocarbon receptor overexpression in miniaturized follicles in female pattern hair loss
Aryl hydrocarbon receptor overexpression found in miniaturized hair follicles in female hair loss.
research TNF-a in nonscarring inflammatory alopecia
TNF-a may not be as involved in certain types of hair loss as previously thought.
research Transcriptional profiling in alopecia areata defines immune and cell cycle control related genes within disease-specific signatures
The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
research A Woman With Nodules and Depressed Scars
The woman has a skin condition involving nodules, scars, and hair loss.
research Accelerated senescence in skin in a murine model of radiation-induced multi-organ injury
High-dose radiation speeds up aging in skin stem cells.
research Research Snippets
New hair regrowth model introduced, imiquimod kills skin cancer cells, T-cadherin loss makes skin cancer more invasive, no strong link between PTCH1 gene and skin cancer after transplant, and male teens more likely to have hereditary hair loss.
research Is female-pattern hair loss an autoimmune-like disorder? Unveiling the “silent” inflammation
Female-pattern hair loss may involve an autoimmune-like process, suggesting new treatment options.
research Congenital atrichia with papular lesions resulting from novel mutations in human hairless gene in four consanguineous families
Mutations in the hairless gene cause a rare form of permanent hair loss.
research p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis
The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.
research Atypical Progeroid Syndrome due to Heterozygous Missense LMNA Mutations
The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.
research A BIOCHEMICAL MARKER IN A DOMINANT MOUSE TRAIT
The Naked (N) trait in mice is linked to lower glycine and tyrosine in hair proteins.
research Alterations in the expression of specific epidermal keratin markers in the hairless mouse by the topical application of the tumor promoters 2,3,7,8-tetrachlorodibenzo-p-dioxin and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate
TCDD changes skin cell growth and keratin production in mice.
research Histopathology of alopecia areata, acute and chronic: Why is it important to the clinician?
Recognizing the different stages of alopecia areata is crucial for accurate diagnosis and treatment.
research Total and longitudinal body dimensions in Ukrainian men with alopecia areata
Men with alopecia areata have different body proportions, with shorter legs and longer upper bodies.
research 420 Severe thiopurine-induced myelotoxicity and hair loss in Japanese patients with NUDT15 gene variant: A retrospective case-control study
Screening for the NUDT15 gene variant can prevent severe side effects from thiopurine drugs in East-Asian people.
research The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice
Disrupting the Sox21 gene in mice causes hair loss and regrowth cycles.
research The lipide composition of epidermis and dermis of mice undergoing carcinogenesis by methylcholanthrene.
Cholesterol and phospholipids increase in mouse skin during cancer development, with differences between male and female skin.