20 citations
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February 2009 in “Chemistry & Biodiversity” Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.
December 2023 in “European Journal of Pharmacology” C3G and Vitisin A may help prevent hair loss by blocking male hormones and stopping hair cell death.
Bilateral Orchiectomy effectively reduces the need for anti-androgen medication in most transgender females.
March 2023 in “Current Pharmaceutical Design” Spironolactone is effective for idiopathic hirsutism but has limited effects on other PCOS symptoms.
January 1989 in “Oxford University Research Archive (ORA) (University of Oxford)” Spironolactone effectively reduces unwanted hair growth in women with hirsutism.
16 citations
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September 1964 in “The journal of investigative dermatology/Journal of investigative dermatology” New compounds can block testosterone effects in rats and might help treat conditions like prostate cancer and acne.
78 citations
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May 1989 in “The Journal of Clinical Endocrinology & Metabolism” Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.
27 citations
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July 1982 in “British Journal of Dermatology” The antiandrogen 11α-hydroxyprogesterone effectively reduces skin oil and cholesterol when applied to the skin.
90 citations
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July 2009 in “PTR. Phytotherapy research/Phytotherapy research” Spearmint tea may reduce testosterone and self-reported hair growth in women with PCOS.
11 citations
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June 2016 in “European Journal of Medicinal Chemistry” Compounds 6f and 6g effectively stop prostate cancer cell growth without harming healthy cells.
8 citations
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January 1987 in “Gynecological Endocrinology” Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.
17 citations
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January 1984 in “Psychotherapy and psychosomatics” Antiandrogen treatment can reduce sexual enjoyment in women with excess male hormones, especially those in stable relationships.
May 2022 in “Endocrine Abstracts” Cyproterone acetate therapy improved hair loss and reduced testosterone levels in a menopausal woman.
37 citations
,
November 2002 in “Biology of Reproduction” Prenatal antiandrogen treatment altered hormone levels in adult spotted hyenas, affecting males and females differently.
Oral contraceptives and antiandrogens are the best treatments for hirsutism.
July 2023 in “Assiut Veterinary Medical Journal/Maǧallaẗ Asyūṭ al-ṭibiyyaẗ al-baytariyyaẗ” Antiandrogens help improve developmental delays caused by valproic acid in rats.
3 citations
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December 2024 in “EClinicalMedicine” Anti-androgens are not better than birth control pills for PCOS, but can help with excess hair if pills don't work.
9 citations
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August 2000 in “Journal of Periodontal Research” Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.
75 citations
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March 1999 in “Fertility and sterility” Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.
15 citations
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January 1998 in “Journal of Clinical Periodontology” Finasteride helps treat hair loss by blocking enzyme activity.
September 2012 in “The Egyptian Journal of Histology” Flutamide caused damage to male rat reproductive organs and may affect fertility.
62 citations
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May 1997 in “Journal of Pharmaceutical Sciences” Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.
10 citations
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November 1997 in “British Journal of Dermatology” RU58841 significantly increases hair growth rate and initiates more hair cycles, but doesn't affect hair thickness, suggesting it could be a new treatment for baldness.
September 1978 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” 9 citations
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November 1997 in “British Journal of Dermatology”
44 citations
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March 2012 in “Fitoterapia” Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.
19 citations
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June 1999 in “Steroids” Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
November 2023 in “PubMed” Combining stem cell-conditioned media with anti-androgen drugs can improve hair growth in male pattern baldness.
April 2016 in “The FASEB Journal” Blocking androgen receptors early in life increases estrogen levels and reduces sexual motivation in male rats.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Anti-androgens help manage PCOS symptoms like excess hair and acne.