72 citations
,
January 2003 in “American Journal of Pathology” A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.
71 citations
,
April 2020 in “Journal of Cosmetic Dermatology” Genetic differences may affect COVID-19 deaths; anti-androgens could be potential treatment.
49 citations
,
January 2021 in “Journal of The European Academy of Dermatology and Venereology” Anti-androgens, like finasteride, dutasteride, and spironolactone, may lessen the severity of COVID-19 in men, leading to fewer ICU admissions.
38 citations
,
July 2012 in “international journal of endocrinology and metabolism” Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.
25 citations
,
March 2004 in “Regulatory Toxicology and Pharmacology” Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.
24 citations
,
March 2002 in “Expert opinion on investigational drugs” Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.
24 citations
,
January 2010 in “Annales d'endocrinologie” For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.
18 citations
,
June 2021 in “Endocrinology” Anti-androgens might help reduce COVID-19 severity in men.
16 citations
,
August 2004 in “Tetrahedron” Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
9 citations
,
October 2012 in “Frontiers of Hormone Research” Antiandrogens are the main treatment for hirsutism, with individualized care and safe, affordable options needed.
7 citations
,
August 2023 in “EClinicalMedicine” Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.
7 citations
,
December 2022 in “Plants” Guava leaf extract may help treat hair loss and protect cells by blocking certain genes and fighting damaging molecules.
7 citations
,
September 1988 in “Baillière's clinical obstetrics and gynaecology” Cyproterone acetate is effective for treating hirsutism and acne in women by blocking androgens in the skin and also works as a contraceptive.
5 citations
,
December 1979 in “Clinical and Experimental Dermatology” Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.
5 citations
,
October 2010 in “General and Comparative Endocrinology” Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.
4 citations
,
January 1991 in “Journal of obstetrics and gynaecology” The photographic method accurately measures hair growth and both treatments effectively reduced hair growth in hirsute women.
4 citations
,
April 2016 in “Journal of Dermatology Research and Therapy” Anti-androgens are safe and effective for treating moderate to severe adult female acne.
1 citations
,
December 2019 in “Current Medicinal Chemistry” Anti-androgen drugs can help reduce OCD symptoms, but more large-scale trials are needed to confirm their effectiveness.
1 citations
,
January 2007 in “Humana Press eBooks” Effective treatments for excessive body hair in women include drugs that block androgens, sometimes combined with oral contraceptives.
1 citations
,
January 1989 in “Handbook of experimental pharmacology” Anti-androgens can help reduce the effects of male hormones on the skin.
1 citations
,
January 1979 in “International Journal of Dermatology” Cyproterone acetate effectively treats hirsutism and related conditions.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Anti-androgens help manage PCOS symptoms like excess hair and acne.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Anti-androgens help manage PCOS symptoms like excess hair and acne.
Bilateral Orchiectomy effectively reduces the need for anti-androgen medication in most transgender females.
Anti-androgens can help treat tough skin conditions like severe acne and excessive hair growth.
Cyproterone acetate with ethynyl estradiol significantly improved acne and seborrhea in women, but was less effective for hair loss and excessive hair growth.
May 2025 in “Journal of the American Academy of Dermatology” Oral and topical anti-androgens can help treat female hair loss, but have side effects.
Bicalutamide does not significantly affect liver enzymes and is a safe anti-androgen option for transfeminine individuals.
20 citations
,
February 2009 in “Chemistry & Biodiversity” Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.
5 citations
,
January 2021 in “Biomedicine & Pharmacotherapy” Policosanol helps treat hair loss by balancing hormones and supporting hair growth.