157 citations
,
May 2021 in “Endocrine Reviews” Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.
151 citations
,
February 2007 in “International Journal of Dermatology” Alopecia areata causes hair loss, has no cure, and various treatments exist.
141 citations
,
September 2016 in “European Journal of Dermatology” Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.
139 citations
,
December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
131 citations
,
August 2004 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.
131 citations
,
August 2000 in “International Journal of Dermatology” Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
125 citations
,
August 2020 in “Frontiers in Immunology” Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
123 citations
,
November 2012 in “Stem cells” MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.
122 citations
,
November 1984 in “Journal of the American Academy of Dermatology” No single treatment is consistently effective for alopecia areata, and more research is needed.
116 citations
,
December 2017 in “International Journal of Women's Dermatology” Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.
115 citations
,
August 2008 in “The Journal of Clinical Endocrinology & Metabolism” Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.
114 citations
,
January 2007 in “Drug Safety” Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.
113 citations
,
July 2020 in “Communications biology” Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.
109 citations
,
October 2007 in “Journal of pineal research” Melatonin helps regulate hair growth and protects the hair follicle from stress.
105 citations
,
February 2017 in “British Journal of Dermatology” Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.
101 citations
,
July 2020 in “Dermatologic therapy” COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.
99 citations
,
October 2006 in “BMC clinical pharmacology” Finasteride may cause slight depression and anxiety.
98 citations
,
October 2012 in “Dermatologic Clinics” Eating the right nutrients can improve hair health, but taking extra supplements usually doesn't help unless you have a deficiency.
98 citations
,
May 2008 in “British Journal of Dermatology” There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.
98 citations
,
August 2007 in “PLoS ONE” Myc changes chromatin in stem cells, causing them to leave their niche.
96 citations
,
September 2008 in “Seminars in Cutaneous Medicine and Surgery” Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.
95 citations
,
January 2012 in “British Journal of Dermatology” Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.
93 citations
,
February 2015 in “Journal of Investigative Dermatology” Oxidative stress affects hair loss in men with androgenetic alopecia.
87 citations
,
July 2012 in “Expert Review of Clinical Immunology” Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.
86 citations
,
October 2017 in “Translational pediatrics” Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.
86 citations
,
May 2005 in “Seminars in Arthritis and Rheumatism” Kawasaki Disease is rare and often missed in adults, who show different symptoms than children, and may benefit from early treatment.
85 citations
,
October 2012 in “Dermatologic Clinics” Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.
84 citations
,
December 2018 in “Genetics in Medicine” Pegvaliase is recommended for treating adults with phenylketonuria.
84 citations
,
March 2010 in “Infectious Disease Clinics of North America” The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.
77 citations
,
June 2015 in “Nature Reviews Urology” Some common medications can harm male fertility, but many effects can be reversed.