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December 2015 in “Neuroendocrinology” Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.
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January 2017 in “Orphanet journal of rare diseases” FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
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January 1990 in “Clinical Endocrinology” Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
31 citations
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January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
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August 2021 in “Oncogene” miR-22 helps skin cancer grow and spread by activating specific cell signals.
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July 2019 in “PloS one” Patients with Alopecia areata have fewer specific immune cells that normally regulate the immune system, which may contribute to the condition.
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April 2002 in “Archives of Dermatology” Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.
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January 2000 in “Dermatologic Clinics” Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
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May 1991 in “Psychosomatics” Some psychiatric medications can cause reversible hair loss.
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May 2018 in “Clinical Endocrinology” Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.
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June 2013 in “Journal of the Saudi Society of Dermatology & Dermatologic Surgery” Alopecia areata is an autoimmune hair loss condition treated with corticosteroids, and histologic confirmation is the best diagnosis method.
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October 2012 in “Anais Brasileiros De Dermatologia” Diagnosing hair loss disorders needs clinical, dermoscopic, and histological differences, and checking menstrual cycle, weight changes, drug therapy, and nail changes.
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January 2012 in “Biological & pharmaceutical bulletin” Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.
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July 2007 in “Development” TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
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March 2024 in “Frontiers in Pharmacology” Natural products can help overcome cancer drug resistance.
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March 2019 in “PLoS ONE” Thyroxine (T4) may help heal skin wounds by promoting new skin and blood vessel growth.
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May 2017 in “Marine Drugs” Undariopsis peterseniana extract helps hair grow by activating certain cell growth pathways and could be a new treatment for hair loss.
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December 2016 in “Dermatology and Therapy” Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.
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June 2018 in “The journal of immunology/The Journal of immunology” AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
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May 2020 in “EMBO reports” Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
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January 2014 in “Annals of Dermatology” Sfrp2 increases during hair follicle catagen phase and slows keratinocyte growth.
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April 2020 in “Cells” DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.
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January 2019 in “Theranostics” Loss of Pten in certain hair follicle stem cells increases skin cancer risk.
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March 2017 in “Archives of Gynecology and Obstetrics” The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
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November 2007 in “Journal of Investigative Dermatology Symposium Proceedings” Hair and scalp disorders significantly affect self-esteem, and using cosmetic products like conditioners and styling aids can improve hair health and appearance.
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April 2021 in “Journal of Clinical Medicine” Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
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January 2010 in “Journal of Medical Primatology” Hair loss in Rhesus macaques may be caused by a skin allergy-related condition.
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June 2012 in “PLOS ONE” Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.