research Antiandrogenic drugs, a therapeutic option for frontal fibrosing alopecia patients
Antiandrogenic drugs could be a good treatment option for frontal fibrosing alopecia.
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research Antiandrogen Drugs Lower Serum Prostate-Specific Antigen (PSA) Levels in Hirsute Subjects: Evidence That Serum PSA Is a Marker of Androgen Action in Women1
Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.
research Can we halt male androgenetic alopecia progression without antiandrogenic drugs?
Only anti-androgenic drugs likely halt AGA progression.
research Bicalutamide: A potential new oral antiandrogenic drug for female pattern hair loss
Bicalutamide may be a promising alternative treatment for female pattern hair loss.
research Spironolactone: An Anti-androgenic and Anti-hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19
Spironolactone might help protect against severe lung problems in COVID-19 patients.
research The Effect of Mesenchymal Stem Cells Derived-Conditioned Media in Combination with Oral Anti-Androgenic Drugs on Male Pattern Baldness: An Animal Study.
Combining stem cell-conditioned media with anti-androgen drugs can improve hair growth in male pattern baldness.
research Drug interactions between common dermatological medications and the oral anti-COVID-19 agents nirmatrelvir-ritonavir and molnupiravir
Some skin medications can have harmful interactions with the COVID-19 drug nirmatrelvir-ritonavir, but not with molnupiravir.
research Repurposing existing drugs for COVID-19: an endocrinology perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Drug-induced gynecomastia: A systematic review and meta-analysis of randomized clinical trials
Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.
research Efficacy, safety and tolerability of drugs for alopecia: a comprehensive review
Future alopecia treatments will improve with targeted therapies and personalized approaches.
research Novel Strategies for Androgenetic Alopecia Therapy: Integrating Multifunctional Plant Extracts with Nanotechnology for Advanced Cutaneous Drug Delivery
Combining plant extracts with nanotechnology may improve hair loss treatments.
research Polycystic Ovary Syndrome: A Comprehensive Review of Pathogenesis, Management, and Drug Repurposing
PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
research Inhibition of SARS-CoV-2 entry through the ACE2/TMPRSS2 pathway: a promising approach for uncovering early COVID-19 drug therapies
Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.
research Frontal fibrosing alopecia: A multicenter review of 355 patients
Most patients with frontal fibrosing alopecia are postmenopausal women, and treatments like finasteride and dutasteride can improve or stabilize the condition.
research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
research Follicular delivery of spironolactone via nanostructured lipid carriers for management of alopecia
Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.
research Steroid 5α-Reductase Inhibitors
New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
research Targets to treat androgen excess in polycystic ovary syndrome
The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
research Poria cocos polysaccharides attenuate chronic nonbacterial prostatitis by targeting the gut microbiota: Comparative study of Poria cocos polysaccharides and finasteride in treating chronic prostatitis
Poria cocos polysaccharides and finasteride both help treat chronic nonbacterial prostatitis, but Poria cocos polysaccharides also improve gut health.
research Frontal fibrosing alopecia
Hormonal imbalances may play a role in frontal fibrosing alopecia, and antiandrogenic drugs combined with steroids are currently the most effective treatment.
research Frontal fibrosing alopecia in men: A multicenter study of 39 patients
Most men with Frontal fibrosing alopecia also lose facial hair and the condition may be linked to hormone levels and sunscreen use.
research Reply to ‘Frontal fibrosing alopecia’
Smoking doesn't cause or prevent Frontal Fibrosing Alopecia, hormonal imbalance may be involved, and a combination of antiandrogens and steroids can help stabilize the condition.
research Efeitos de diferentes doses do Minoxidil oral, em dois tempos de exposição, no complexo prostático de camundongos Balb/C
Oral minoxidil affects prostate tissue but is less harmful than finasteride.
research Reduction of Diameter of Hair Shaft among Women with Hirsutism
Aldactone effectively reduces hair thickness in women with excessive hair growth, both alone and with other treatments.
research Reduction of Diameter of Hair Shaft among Women with Hirsutism
Spironolactone effectively makes hair shafts thinner in women with excessive hair growth.
research Frontal fibrosing alopecia: Histopathological and immunohistochemical study of the inflammatory infiltrate and the sebaceous gland receptors
Frontal fibrosing alopecia may be caused by an autoimmune reaction and hormonal imbalance.
research [G-proteins, receptor signal transduction, and growth hormone secretion].
The document concludes that antiandrogenic drugs like cyproterone acetate and spironolactone are effective but not permanent treatments for skin-related androgenization in women.
research The antiandrogen enzalutamide downregulates TMPRSS2 and reduces cellular entry of SARS-CoV-2 in human lung cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
research Comparison of spironolactone and spironolactone plus finasteride in the treatment of hirsutism
Spironolactone plus finasteride works better for treating hirsutism.
research UPDATE ON IDIOPATHIC HIRSUTISM: DIAGNOSIS AND TREATMENT
The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.