July 2021 in “Advances in laboratory medicine” Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.
June 2021 in “International Journal of Ayurvedic Medicine” Phytoconstituents from Cyperus Rotundus may help treat hirsutism by interacting with the 5 α reductase enzyme.
June 2021 in “Pharmaceutical sciences” Flutamide emulgel with 1% Transcutol P absorbs better through the skin than other mixtures.
November 2020 in “Journal of The American Academy of Dermatology” Men with male pattern baldness may be more at risk for severe COVID-19, and anti-androgen treatments could offer protection.
January 2018 in “Modern approaches in drug designing” Kunzea oil may help stimulate hair growth.
Saw palmetto is not proven to improve urinary flow, prostate size, or hair loss.
Thai plant extracts, especially Avicennia marina, can promote hair growth by inhibiting certain enzymes and boosting growth factors.
Some plants may help with hair growth but need more scientific evidence.
September 2005 in “Morecambe Bay medical journal” Insulin resistance plays a key role in PCOS, and lifestyle changes, weight loss, and medications like metformin can help manage it.
January 2004 in “Elsevier eBooks” Anti-androgen drugs can treat conditions like prostate cancer and male pattern baldness by blocking effects of testosterone and DHT.
January 2020 in “The Journal of Sexual Medicine” Using 5α-reductase inhibitors for hair loss can cause lasting sexual, physical, mental, and vascular health issues in men, even after stopping the medication.
August 2018 in “Farmatsevtychnyĭ zhurnal” The emulgel with Saw Palmetto and Sophora Japonica shows promise for treating hair loss.
341 citations
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November 2009 in “The FASEB Journal” Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.
129 citations
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October 2007 in “The New England Journal of Medicine” Over one-third of women experience hair loss, with female-pattern hair loss being most common, and treatments include minoxidil and possibly hair transplantation.
121 citations
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April 2008 in “The Journal of Clinical Endocrinology & Metabolism” Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.
78 citations
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February 2011 in “Canadian Medical Association Journal” Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.
75 citations
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June 2019 in “International Journal of Molecular Sciences” Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.
74 citations
,
November 1975 in “Archives of dermatology” Increased DHT formation in skin can cause hair loss, acne, and excessive hair growth, and antiandrogens might treat these conditions.
68 citations
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April 2014 in “Journal of Molecular Endocrinology” The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.
58 citations
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March 1985 in “Journal of The American Academy of Dermatology” The document concludes that electrolysis and thermolysis can permanently remove hair but calls for better regulation to ensure safety, and notes a possibility of hair regrowth and rare complications.
57 citations
,
October 2013 in “international journal of endocrinology and metabolism” Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.
52 citations
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January 2003 in “Journal of Investigative Dermatology” Thrombospondin-1 is crucial for hair follicle regression and reduced blood vessel growth during the catagen phase.
51 citations
,
September 2015 in “Medical Clinics of North America” The conclusion is that acne, alopecia, and hyperhidrosis are common skin issues with various treatments available, and accurate diagnosis is key for effective management.
48 citations
,
January 2014 in “Dermatology Online Journal” New treatments for Dissecting cellulitis show promise, but more research is needed to understand the disease and establish a standard treatment plan.
47 citations
,
July 2016 in “Current pharmaceutical design” The document concludes that managing hirsutism in PCOS involves long-term treatment guided by severity, using oral contraceptives and possibly antiandrogens, with attention to individual patient needs.
43 citations
,
December 1993 in “Annals of internal medicine” Flutamide, a medication used for excessive hair growth, can cause severe liver damage in women.
43 citations
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July 1984 in “Clinical and Experimental Dermatology” Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.
42 citations
,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
36 citations
,
September 2014 in “Paediatric drugs” More pediatric-specific research and guidelines are needed to improve hidradenitis suppurativa treatment in children and adolescents.
34 citations
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March 2001 in “Cleveland Clinic Journal of Medicine” Manage hair shedding by identifying triggers, possibly using supplements or medications, and tracking with a health calendar.