Search

for
Search:

Did you mean Antiandrogenic Effects?

GlossaryAntiandrogenic Effects

inhibit male sex hormones like testosterone

Antiandrogenic effects refer to the actions of substances that inhibit the effects of androgens, which are male sex hormones like testosterone. These substances can block androgen receptors or reduce androgen production, and are often used in treatments for conditions like prostate cancer, androgenic alopecia (male-pattern baldness), and hirsutism (excessive hair growth in women).

Related Terms

Sort by

Research

30 / 1000+ results

research Therapeutic effect of finasteride through its antiandrogenic and antioxidant role in a propionic acid-induced autism model: Demonstrated by behavioral tests, histological findings and MR spectroscopy

3 citations , April 2022 in “Neuroscience Letters”

Finasteride may help treat autism by reducing inflammation and oxidative stress.

research Anti-invasive effects of minoxidil on human breast cancer cells: combination with ranolazine

5 citations , May 2022 in “Clinical & Experimental Metastasis”

Minoxidil and ranolazine together can reduce the spread of certain breast cancer cells.

research The antiandrogenic effect of finasteride against a mutant androgen receptor

20 citations , May 2011 in “Cancer Biology & Therapy”

Finasteride may improve prostate cancer treatment outcomes.

research Evaluating Antiinflammatory and Antiandrogenic Effects of Garden Cress (Lepidium sativum L.) in HaCaT cells

5 citations , June 2018 in “Records of Natural Products”

Garden cress extract may help treat skin inflammation and androgen-related disorders.

Research Brief: Self-Reports of Persistent Antiandrogenic, Estrogenic, Physical, and Psychological Effects of Finasteride Usage Among Men

research Research Brief: Self-Reports of a Constellation of Persistent Antiandrogenic, Estrogenic, Physical, and Psychological Effects of Finasteride Usage Among Men

9 citations , January 2018 in “American Journal of Men's Health”

Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.

research Unusual Anti-Angiogenic Effect of Combined Hormonal Blockade

1 citations , October 2002 in “The Journal of Urology”

research Antiaging effects of equol: A unique antiandrogenic isoflavone metabolite and its influence in stimulating collagen deposition in human dermal monolayer fibroblasts

2 citations , March 2005 in “Journal of the American Academy of Dermatology”

Equol may help with antiaging and skin health by boosting collagen and blocking certain hormones.

Evaluation of Derma Genie-H001 as a Functional Cosmetic Ingredient for Hair Loss Improvement: Assessing Anti-Inflammatory, Antioxidative, Photoprotective, Antiandrogenic, and Hair Growth-Inductive Effects

research Evaluation of Derma Genie™-H001 as a Functional Cosmetic Ingredient for Hair Loss Improvement: Assessing Anti-inflammatory, Antioxidative, Photoprotective, Antiandrogenic, and Hair Growth-Inductive Effects

March 2024 in “Asian journal of beauty & cosmetology”

Derma Genie™-H001 can help prevent hair loss and promote hair growth.

research The effects of two doses of spironolactone on serum androgens and anagen hair in hirsute women

142 citations , February 1985 in “Fertility and sterility”

Spironolactone reduced hair thickness and some testosterone levels in women with excessive hair growth.

research Lack of Effect of a Spironolactone-Containing Cream on Hair Growth in Hirsute Women

16 citations , January 1987 in “Dermatology”

The spironolactone cream did not reduce hair growth in women with hirsutism.

research Reversal of andro-genetic alopecia in a male. A spironolactone effect?

3 citations , July 1990 in “Acta dermato-venereologica”

A man's baldness improved possibly due to a medication that blocks male hormones.

research Mixed “Antiandrogenic” Chemicals at Low Individual Doses Produce Reproductive Tract Malformations in the Male Rat

49 citations , March 2018 in “Toxicological sciences”

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

Inhibitory Effects of Serenoa Repens on the Kinetics of Pig Prostatic Microsomal 5α-Reductase Activity

research Inhibitory Effects of Serenoa repens on the Kinetic of Pig Prostatic Microsomal 5α-Reductase Activity

12 citations , January 1998 in “Endocrine journal”

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

research [Reactions and side effects of ovulation inhibitors on the skin].

January 1978 in “PubMed”

Oral contraceptives can affect skin and hair, improve acne, but may cause pigmentation, dermatitis, and other conditions.

research Dermatologic Side Effects of Systemic Targeted Anticancer Therapy

January 2018 in “Springer eBooks”

Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.

research Skin toxicity of anti‐cancer therapy

19 citations , October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft”

Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.

research Effect of Ficus carica leaf extract on the gene expression of selected factors in HaCaT cells

16 citations , April 2017 in “Journal of Cosmetic Dermatology”

Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.

research Effect of Carbamates on mRNA Encoding Lipid Enzymes in Hamster Flank Organs

1 citations , February 2014 in “Archiv Der Pharmazie”

Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.

research Novel C-6 substituted and unsubstituted pregnane derivatives as 5α-reductase inhibitors and their effect on hamster flank organs diameter size

15 citations , May 2009 in “Steroids”

Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.

Differentiated Application of Oral Contraceptives Based on the Different Side Effects of Synthetic Progestins

research [Differentiated application of oral contraceptives basing on the different side effects of synthetic progestins (author's transl)].

April 1976 in “PubMed”

Choose oral contraceptives with specific side effects to manage issues like acne and avoid unwanted effects.

research 17-Oximino-5-androsten-3β-yl esters: synthesis, antiproliferative activity, acute toxicity, and effect on serum androgen level

7 citations , August 2010 in “Medicinal Chemistry Research”

Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.

Focus on Finasteride: Efficacy, Mechanisms, and Recommendations for Clinical Use

research Focus sulla finasteride: efficacia, meccanismi e raccomandazioni per l'uso clinico

March 2026 in “Gazzetta Medica Italiana Archivio per le Scienze Mediche”

Finasteride effectively treats benign prostatic hyperplasia by reducing prostate size and improving urinary symptoms.

research Cosmeceutical and Dermatological Potential of Olive Mill Wastewater: A Sustainable and Eco-Friendly Source of Natural Ingredients

4 citations , July 2025 in “Cosmetics”

Olive mill wastewater can be used as a sustainable source of skin-benefiting ingredients.

research Cosmetic and Dermatological Properties of Olive Oil Byproduct-Supplemented Skin and Hair Care Products

May 2025 in “Preprints.org”

Olive oil byproducts can be used in skincare for their antioxidant and protective benefits.

research A Novel Use of Spironolactone: Treatment of Hirsutism

124 citations , September 1980 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

Spironolactone is effective in treating excessive hair growth in women.

research Spironolactone Therapy for Hirsutism in a Hyperandrogenic Woman

39 citations , November 1978 in “Annals of internal medicine”

Spironolactone may help reduce excessive hair growth in women with high male hormone levels.

research Interaction of spironolactone with rat skin androgen receptor

23 citations , July 1979 in “Canadian journal of biochemistry”

Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.

research Topical Antiandrogens

11 citations , January 1985 in “Archives of Dermatology”

Topical antiandrogens might treat skin issues like hair growth, balding, and acne, but finding effective treatments without side effects is challenging.

Use of Spironolactone in Dermatology: Acne, Hidradenitis Suppurativa, Female Pattern Hair Loss, and Hirsutism

research Uso de la espironolactona en dermatología: acné, hidradenitis supurativa, alopecia femenina e hirsutismo

9 citations , June 2020 in “Actas Dermo-Sifiliográficas”

Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.

research Use of spironolactone in dermatology.

9 citations , April 2011 in “PubMed”

Spironolactone is used in dermatology to treat skin conditions related to hormones, but is not safe for pregnant women or men.