2 citations
,
July 2019 in “Digital Showcase Research, Scholarship, & Creative Works (University of Lynchburg)” No proven link between isotretinoin and depression.
December 2025 in “The Journal of Clinical Psychiatry” Finasteride can cause depression and suicidal thoughts; safer alternatives are recommended.
2 citations
,
September 2009 in “Hormone Molecular Biology and Clinical Investigation” Low dose finasteride decreases certain steroids, possibly increasing depression risk.
110 citations
,
August 2015 in “Neuropsychopharmacology” High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
1 citations
,
August 2017 in “The Journal of urology/The journal of urology” 5α-reductase inhibitors may increase the risk of depression and suicidal thoughts.
May 2024 in “European urology focus” Drugs for prostate enlargement and hair loss were not linked to increased risk of depression or suicide.
January 2017 in “ScholarWorks - WMU (Western Michigan University)” Stopping SSRIs can reverse hair loss in some patients.
2 citations
,
June 2022 in “INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine)” Vitamin D can help reduce depression in people with hypothyroidism.
January 2026 in “Frontiers in Medicine”
May 2025 in “Psychopharmacology” Chronic finasteride use in male rats doesn't strongly cause depression or anxiety due to adaptive stress hormone changes.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Acne treatment, including isotretinoin, improves quality of life and does not worsen depression.
June 2024 in “Drug and therapeutics bulletin” Finasteride can cause depression, suicidal thoughts, and lasting psychiatric and sexual issues.
1 citations
,
November 2022 in “INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine)” Vitamin D helps reduce depression in people with autoimmune thyroiditis and hypothyroidism.
January 2012 in “The Journal of Clinical Psychiatry” 11 citations
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November 2011 in “Neuroreport” Paroxetine relieves pain by increasing allopregnanolone levels.
November 2023 in “Magna Scientia Advanced Research and Reviews” Trazodone might help reverse post finasteride syndrome.
March 2025 in “Journal of Cosmetic Dermatology” Finasteride use may increase depression and suicide risk, especially at 1 mg, so monitoring is advised.
September 2025 in “The Journal of Clinical Psychiatry” Finasteride may increase depression and suicide risks, needing better safety checks and informed consent.
10 citations
,
December 2014 in “PubMed” Finasteride, a hair loss drug, may cause sexual dysfunction and depression, but these effects are usually temporary and the drug is generally safe. More research is needed.
27 citations
,
April 2008 in “Neuroscience Letters” Olanzapine reduces stress-related anxiety in rats when given acutely.
December 2023 in “Alzheimer's & dementia” Finasteride may help reduce anxiety and depression in elderly but might cause depression in young men.
Finasteride may cause depression and affect brain and gut health in male rats.
June 2017 in “Reactions Weekly” Finasteride (Propecia) may cause depression and suicidal thoughts; stop use and inform a healthcare professional if symptoms develop.
3 citations
,
February 2019 in “Der Urologe” Medications for benign prostatic syndrome can cause cognitive issues and depression.
January 2020 in “Journal of quality in health care & economics” Most women with depression in the study had low vitamin D levels.
4 citations
,
May 2019 in “The World Journal of Men's Health” Taking 5 alpha reductase inhibitor medication slightly increases the risk of depression, especially as you get older.
1 citations
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May 2023 in “Ayna Klinik Psikoloji Dergisi” Alopecia Areata is linked to higher depression levels.
October 2025 in “Reactions Weekly” Finasteride and dutasteride may cause depression and suicidal thoughts.