April 2022 in “The Journal of Sexual Medicine” Finasteride alone increases suicide risk, but combining it with other treatments reduces this risk.
December 2006 in “The Brown University Psychopharmacology Update” Second-generation antipsychotics offer no significant benefit over first-generation ones for schizophrenia.
24 citations
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July 2015 in “International Journal of Molecular Sciences” Fluoxetine may help reduce fat by limiting stem cell growth and fat cell formation.
July 2025 in “Reactions Weekly” August 2016 in “Psychoneuroendocrinology”
November 2020 in “Reactions Weekly” Finasteride can cause lasting erectile dysfunction, low libido, and depression in some patients.
5 citations
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January 2012 in “Psychology” Depression may be linked to changes in body electrolytes and muscle inactivity, similar to effects of weightlessness.
1 citations
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May 2024 in “Journal of Clinical Medicine” Depression and skin autoimmune diseases are linked, needing combined care for better treatment.
January 2013 in “Psychiatry and clinical neurosciences” Physical symptoms in depression can reveal underlying medical conditions.
May 2025 in “Reactions Weekly” 4 citations
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April 2009 in “Journal of Pain” Finasteride boosts morphine's pain relief and prevents tolerance and withdrawal in rats.
February 2025 in “Ciencia Latina Revista Científica Multidisciplinar” Finasteride can help with hair loss and prostate issues but may negatively affect mood and the nervous system.
July 2009 in “Guoji yiyao weisheng daobao” Combining α1A-blockers with Prozac is more effective for treating premature ejaculation than Prozac alone.
19 citations
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January 2012 in “Frontiers in Neural Circuits” Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.
December 2013 in “Reactions Weekly” Some men taking finasteride for hair loss experienced anxiety, depression, and sexual problems, which sometimes continued after stopping the medication.
April 2023 in “Journal of Investigative Dermatology” Narrowband Ultraviolet B treatment can significantly reduce anxiety in psoriasis patients, but it doesn't significantly affect depression.
December 2015 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Finasteride, a hair loss treatment, may cause long-term sexual dysfunction and depression.
April 2019 in “International research journal of pharmacy” Adiantum capillus extract reduces pain and swelling in animals.
September 2025 in “Reactions Weekly” September 2025 in “Journal of the American Academy of Dermatology” Deuruxolitinib improves anxiety and depression in severe alopecia areata patients.
83 citations
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July 2004 in “Pharmacology Biochemistry and Behavior” Higher 3α,5α-THP levels in the brain may reduce depression in pregnant rats.
10 citations
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January 2017 in “Skin Pharmacology and Physiology” Finasteride may cause vitiligo, sexual issues, and depression; better treatments and predicting side effects needed.
May 2022 in “The Journal of Sexual Medicine” Amoxapine may be effective for treating ejaculatory dysfunction.
1 citations
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October 2011 in “Hospital Pharmacy” March 2021 in “Iranian journal of public health” 2 citations
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January 2015 in “Journal of Investigative Dermatology”
1 citations
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May 2022 in “Research Square (Research Square)” Acetate helps reduce depression in rats with PCOS by lowering specific gene expression and DNA changes in the brain.
October 2010 in “Journal of Men's Health” Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
February 2026 in “Cureus” Testosterone therapy had limited benefits for a man with depression and suspected low testosterone, highlighting the need for careful diagnosis and treatment planning.
December 2023 in “Alzheimer's & Dementia” Long-term use of a drug for hair loss and prostate issues can cause metabolic problems and depression-like behavior in young male rats.