research Psychotropic Treatment of Psychodermatologic Disorders
Psychotropic drugs can help treat skin conditions affected by mental health, but dermatologists must use them carefully due to side effects and patient concerns.
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research A New Look at the 5?-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
research Somatization in the dermatology patient: Some sociocultural perspectives
Skin symptoms without a medical cause often reflect psychological stress and are influenced by culture, requiring a team approach for treatment.
research Patients treated for male pattern hair with finasteride show, after discontinuation of the drug, altered levels of neuroactive steroids in cerebrospinal fluid and plasma
Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
research Neuroactive steroid levels and psychiatric and andrological features in post-finasteride patients
Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.
research Pathophysiology of the Behçet's Disease
Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.
research Current Literature Review
The document suggests that finasteride may cause depression and suicidal thoughts, while prostate surgery does not harm sexual health.
research Post-finasteride syndrome: An emerging clinical problem
Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.
research Post-finasteride syndrome
Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
research Dehydroepiandrosterone for women in the peri- or postmenopausal phase
DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.
research Advances in male hormone substitution therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research What is the Rationale for Androgen Therapy for Women?
Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.
research Drug‐Induced Liver Failure Following Topical Minoxidil: A Case Report
Topical minoxidil can cause severe liver failure.
research International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women
Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
research Clinical review of ejaculatory dysfunction
The review suggests new ways to classify ejaculation problems and recommends different treatments based on the type of issue.
research Progesterone Promotes Anti-Anxiety/Depressant-like Behavior and Trophic Actions of BDNF in the Hippocampus of Female Nuclear Progesterone Receptor, but Not 5α-Reductase, Knockout Mice
Progesterone reduces anxiety and depression in female mice by increasing BDNF in the brain, needing 5α-reduction and estradiol.
research International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women
Testosterone therapy is effective and safe for women with low sexual desire, but it's hard to access.
research Finasteride interferes with prostaglandin-induced CatSper signalling in human sperm
Finasteride may affect male fertility by interfering with specific sperm signaling.
research Overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus produced anxiolytic and antidepressant-like behavioural effects
Increasing TSPO in the brain reduces anxiety and depression.
research Witnessed trauma exposure induces fear in mice through a reduction in endogenous neurosteroid synthesis
Reduced neurosteroid production increases fear in mice, suggesting potential PTSD treatments.
research Immunohistochemical Evaluation of Androgen Receptor and Nerve Structure Density in Human Prepuce from Patients with Persistent Sexual Side Effects after Finasteride Use for Androgenetic Alopecia
Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.
research Post-finasteride syndrome – does it really exist?
Post-finasteride syndrome's existence is uncertain; more research needed.
research The safety of 52 weeks of oral DHEA therapy for postmenopausal women
Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.
research Antiandrogens and Androgen Inhibitors
Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
research The North American Menopause Society Recommendations for Clinical Care of Midlife Women
The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.
research Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Licorice: A review on phytochemical insights and therapeutic potential
Licorice has health benefits but can also cause side effects, so it should be used carefully.
research Pathophysiological mechanisms implicated in postpartum depression
Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.
research Adverse effects of common medications on male fertility
Some common medications can harm male fertility, but many effects can be reversed.
research The nocebo effect: A clinicians guide
Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.