research Plasticity of GABAergic Inhibition
Targeting specific GABA receptors may help treat epilepsy and postpartum depression.
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330-360 / 1000+ resultsresearch Short-term efficacy and safety of valproate sustained-release formulation in newly diagnosed partial epilepsy VIPe-study. A multicenter observational open-label study.
Valproate sustained-release is effective and generally safe for short-term treatment of new partial epilepsy.
research Table of Contents
Second-generation antipsychotics offer no significant benefit over first-generation ones for schizophrenia.
research Role of Neurosteroidogenic Pathways in the Antiseizure Activity of Midazolam in the 6‐Hz and Kindling Models of Epilepsy
Midazolam's antiseizure effects are mainly due to synaptic GABA-A receptors, not neurosteroids or extrasynaptic receptors.
research Pancreatitis associated with valproic acid therapy for epilepsy
Valproic acid can cause serious side effects, including pancreatitis and even death.
research Faculty Opinions recommendation of Finasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis.
research Transcranial focused ultrasound-mediated unbinding of phenytoin from plasma proteins for suppression of chronic temporal lobe epilepsy in a rodent model
Using focused ultrasound on the brain can help epilepsy medicine work better in rats.
research Hypertensive urgency in a child with focal epilepsy: Is it sodium valproate induced?
Sodium valproate can cause serious high blood pressure in children.
research Side effects of carbamazepine, valproate and clonazepam during long-term treatment of epilepsy
Carbamazepine, valproate, and clonazepam can cause mild to serious side effects during long-term epilepsy treatment.
research Topiramate-induced hair loss in a patient using valproate and levetiracetam
research Ferulic acid inhibits catamenial epilepsy through modulation of female hormones
Ferulic acid may help control menstrual cycle-related epilepsy by affecting female hormones.
research Glia-derived steroids modulate epileptogenesis in a model of temporal lobe epilepsy
Neurosteroids from glia cells help control seizure development in epilepsy.
research Progesterone-induced spike-wave discharges are inhibited by finasteride
Finasteride blocks progesterone's effect on brain activity linked to epilepsy.
research Alopecia Associated with Gabapentin in the Treatment of Neuropathic Pain
Gabapentin may cause hair loss in patients treated for neuropathic pain.
research Telogen Effluvium Caused by Magnesium Valproate and Lamotrigine
Two people lost a lot of hair because of epilepsy drugs, but their hair grew back after changing medication.
research 452: HAIR-RAISING TOXICITY: STATUS EPILEPTICUS FOLLOWING HAIR RESTORATION DUE TO LAST AND TXA TOXICITY
Hair restoration can cause severe seizures due to combined drug toxicity.
research [Visual field defect in a patient given sodium valporate then carbamazepine: possible effect of aminotransferase inhibition].
Anti-epileptic drugs may cause visual and hair side effects due to enzyme inhibition, especially in genetically predisposed individuals.
research Anticonvulsant hypocalcaemia.
Long-term use of seizure medications can disrupt calcium metabolism, but this can be treated with vitamin D or UV light and does not affect seizure control.
research Serum and liver tissue biotinidase enzyme activity in rats which were administrated to valproic acid
Valproic acid may cause hair loss by reducing biotinidase enzyme activity in rats.
research A Mouse Kindling Model of Perimenstrual Catamenial Epilepsy
Neurosteroids help reduce seizures, but their withdrawal increases seizure activity.
research Aromatase inhibition by letrozole attenuates kainic acid-induced seizures but not neurotoxicity in mice
Letrozole reduces seizures but not brain damage in mice.
research Antiseizure Medication-Induced Alopecia: A Literature Review
Some antiseizure medications can cause reversible hair loss, with valproate, lamotrigine, and carbamazepine being the most common.
research Electrophysiological and Histopathological Effects of Minoxidil on Penicillin-Induced Epilepsy Model in Rats
Minoxidil did not significantly affect epilepsy in rats.
research 2‐Deoxy‐d ‐glucose enhances tonic inhibition through the neurosteroid‐mediated activation of extrasynaptic GABA A receptors
2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.
research Role of Zinc Supplementation in the Treatment of Levetiracetam-Induced Hair Loss: A Case Series
Zinc supplements may help reduce hair loss caused by levetiracetam without affecting seizure control.
research Alopecia with carbamazepine in two patients with focal seizures
Two patients with epilepsy experienced hair loss after taking the drug carbamazepine.
research Effects of sodium valproate in 100 children with special reference to weight.
Sodium valproate improved epilepsy control but often caused weight gain in children.
research The role of candidate pharmacogenetic variants in determining valproic acid efficacy, toxicity and concentrations in patients with epilepsy
Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.