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The FDA warned about safety issues with remdesivir and tofacitinib, finasteride is linked to suicidality, potent topical corticosteroids increase osteoporosis risk, henna can cause hemolysis in G6PD deficiency, chemotherapeutic agents can cause adverse reactions, drug interactions are common in cancer patients, ketamine can reduce at-risk drinking, high dose of anticholinergics increases dementia risk in Parkinson's patients, and prenatal exposure to second-generation antipsychotics increases pregnancy complications.

Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.

Spironolactone is used in dermatology to treat skin conditions related to hormones, but is not safe for pregnant women or men.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Using high doses and multiple drugs with steroids is risky and should be prevented.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Topical antiandrogens might treat skin issues like hair growth, balding, and acne, but finding effective treatments without side effects is challenging.

Spironolactone effectively reduces symptoms of hyperandrogenism but has some side effects.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Some drugs can cause hair loss or growth, but hair usually returns to normal after stopping the drug.

Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.

Low-dose spironolactone is safe and effective for treating hirsutism.

Spironolactone and metformin work similarly for PCOS symptoms, but more research is needed.

Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.

A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.

Both finasteride and drospirenone effectively manage PCOS symptoms, but drospirenone is more effective in reducing ovarian volume and androgen levels.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Kuntai capsules combined with nilestriol tablets effectively reduce perimenopausal symptoms and improve hormone levels.

Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.

Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.

Old drugs are often used for new, different medical purposes in endocrine pharmacology.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Flaxseed lignans may reduce breast cancer risk in women.

Finasteride effectively inhibits the enzyme steroid 5 alpha-reductase II.

New anti-acne medications are being tested to offer alternatives to current treatments.

Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.

Medicines that lower androgen levels and hair removal treatments help manage excessive hair and acne in women with PCOS.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.