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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Man experienced sexual dysfunction, depression, breast growth, and skin discoloration after taking finasteride for hair loss.

New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.

Sex steroid hormones are essential for reproductive health and overall well-being.

Low-dose flutamide improved hirsutism and satisfaction in women but had common side effects, causing some to stop treatment.

Prenatal pesticide exposure may cause earlier breast development in girls.

Flutamide caused damage to male rat reproductive organs and may affect fertility.

Tamoxifen effectively treats gynecomastia without causing impotence.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

Oestrogens are key for bone growth during puberty in both boys and girls.

Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.

Testosterone treatment may change estrogen receptor methylation in AFAB individuals.

Removing the ovarian tumor improved the woman's hormonal symptoms.

Sex steroids, especially progesterone, can slow down the growth of mouse melanoma cells.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.

Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.

High doses of some contraceptive steroids cause health issues in dogs, but their relevance to humans is unclear.

A postmenopausal woman's facial redness, acne, and excess hair were caused by too much hormone therapy for insomnia, but improved after stopping the treatment.

Hair loss can occur as a side effect of certain breast cancer treatments, but minoxidil can help regrow hair.

Diane® is an effective contraceptive that also helps treat acne and mild hair growth issues.

Estrogen speeds up hair follicle cell death, causing early hair growth cycle changes, but only if a specific receptor is present.

Reducing iron levels didn't improve heart health or metabolism in women with certain ovarian issues.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.