5 citations
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January 2020 in “in Vivo” Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.
14 citations
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September 2015 in “Expert Opinion on Therapeutic Targets” The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
17 citations
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November 2000 in “Journal of the American Pharmaceutical Association” The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.
January 2025 in “Digital Commons - Gardner-Webb University (Gardner–Webb University)” Abusing anabolic steroids can cause serious health problems despite short-term muscle gains.
10 citations
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July 2011 in “Archives of Pharmacal Research”
31 citations
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November 2014 in “Journal of Endocrinological Investigation” Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.
October 2022 in “Biomedicines” Finasteride in male rats causes liver and metabolic issues in their offspring.
9 citations
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May 2011 in “Hormones and Behavior” Allopregnanolone, a progesterone metabolite, helps reduce restraint effects on behavior.
7 citations
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January 2018 in “Reproduction” Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.
August 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair growth supplements do not reduce the effectiveness of the breast cancer treatment tamoxifen.
Testosterone undecanoate can reduce the negative effects of Finasteride on male reproductive health.
56 citations
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April 1998 in “Steroids” Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.
50 citations
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March 2011 in “European Journal of Endocrinology” Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.
5 citations
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December 1979 in “Clinical and Experimental Dermatology” Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.
6 citations
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June 2006 in “International Journal of Gynecological Pathology” A postmenopausal woman's hormone imbalance and symptoms improved after removing benign ovarian tumors.
41 citations
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February 1970 in “Archives of Dermatology” Oral contraceptives can cause skin issues like dark patches, acne, yeast infections, sensitivity to light, spider veins, skin rashes, and hair loss.
32 citations
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May 2013 in “The Journal of Urology” Using finasteride or dutasteride does not increase the risk of male breast cancer.
August 2013 in “Hospital Pharmacy” Certain medications can cause serious side effects, including skin reactions, stroke, muscle disorders, tongue swelling, hair loss in women, and liver failure.
December 2020 in “Research Square (Research Square)” Rare ovarian tumors can cause increased male hormones in postmenopausal women; surgery is an effective treatment.
2 citations
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January 2017 in “Annals of Dermatology” Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.
5 citations
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January 2017 in “Acta Endocrinologica” High androgen levels in postmenopausal women may suggest an ovarian tumor, and removing it can improve heart and metabolic health.
31 citations
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January 1989 in “The Prostate/The prostate” Estradiol and castration reduced prostate cancer development in rats when applied at early stages, but were ineffective after cancer was established.
64 citations
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January 1985 in “Clinical endocrinology” A combination of desogestrel and ethinyl oestradiol effectively reduces hair growth in hirsute women.
June 2024 in “Ecotoxicology and Environmental Safety” Finasteride harms Daphnia magna's reproduction, growth, and metabolism.
65 citations
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April 2007 in “Chemistry and Physics of Lipids” Steroid hormones change the size, charge, and stability of DPPC liposomes.
October 2020 in “Reactions Weekly” Finasteride can cause multiple side effects like tremors, dry skin, and rapid aging.
January 2013 in “Revista Clínica Española” A postmenopausal woman's increased male hormone levels were successfully treated with surgery.
34 citations
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April 2023 in “Climacteric” Gender-affirming hormone therapy affects health risks and requires careful management, especially as transgender individuals age.
November 2017 in “Reactions Weekly” Testosterone undecanoate caused hair loss; finasteride improved it but caused stomach issues for one patient.