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research LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem‐Like Cells

82 citations , July 2012 in “Brain pathology”

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

research The Cutaneous Inflammatory Response to Thermal Burn Injury in a Murine Model

79 citations , January 2019 in “International Journal of Molecular Sciences”

Burn injuries in mice heal similarly to humans, with inflammation and cell changes normalizing over time.

research Hairless Suppresses Vitamin D Receptor Transactivation in Human Keratinocytes

78 citations , November 2005 in “Endocrinology”

Hairless protein can block vitamin D activation in skin cells.

research The role of the microbiome in scalp hair follicle biology and disease

73 citations , April 2019 in “Experimental Dermatology”

The scalp's microorganisms significantly affect hair health and disease.

research Regulatory mutations in TBX3 disrupt asymmetric hair pigmentation that underlies Dun camouflage color in horses

73 citations , December 2015 in “Nature Genetics”

Mutations in TBX3 cause horses to have more even hair color instead of Dun camouflage.

research Protein Microarrays

73 citations , April 2006 in “BioTechniques”

Protein microarrays are highly sensitive tools useful for disease diagnosis and studying proteins.

research Defining the Cellular Environment in the Organ of Corti following Extensive Hair Cell Loss: A Basis for Future Sensory Cell Replacement in the Cochlea

71 citations , January 2012 in “PloS one”

The conclusion is that genetic differences affect how the cochlea heals after hair cell loss, which may challenge the creation of hearing loss treatments.

research Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity

70 citations , August 2006 in “Cancer Research”

AP-1 controls tumor cell type by affecting key signaling pathways.

research OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases

57 citations , January 2019 in “Stem Cell Research & Therapy”

OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.

research Laminin α5 in the keratinocyte basement membrane is required for epidermal–dermal intercommunication

57 citations , May 2016 in “Matrix Biology”

Laminin α5 is essential for skin communication and health.

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