Metformin helps some women with PCOS but isn't effective for weight loss or treating acne.
December 2024 in “American Journal of Case Reports” Underweight women with PCOS can have insulin resistance, and treatment with metformin and dexamethasone can improve symptoms.
24 citations
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July 2019 in “Journal of Obstetrics and Gynaecology” The combination therapy improved PCOS symptoms in both obese and non-obese women, with weight loss in the obese group.
July 2025 in “Journal of Pharmacognosy and Phytochemistry” Plant-based therapies, like Aloe Vera and Cinnamon, may help manage PCOS symptoms with fewer side effects.
January 2017 in “Open Journal of Endocrine and Metabolic Diseases” The document concludes that managing Dunnigan-Type Familial Partial Lipodystrophy involves treating associated health issues and using medications like metformin and leptin replacement.
May 2022 in “The Journal of Clinical Pharmacology” Metformin reduces certain hormone levels in men with early-onset hair loss.
August 2015 in “Evidence Based Women Health Journal (Online)” Inositol was more effective than Metformin in treating symptoms of PCOS in women.
3 citations
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January 2021 in “Journal of Research in Medical Sciences” Certain medications can impact metabolic syndrome, with some improving conditions like high blood sugar and others having no effect.
5 citations
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August 2020 in “Stem Cell Research & Therapy” Using fat-derived stem cells with the drug meglumine antimoniate can help control skin disease and reduce parasites in mice with leishmaniasis.
January 2010 in “The Year book of dermatology” Taking metformin with intense pulsed light therapy improves hair removal for women with PCOS.