19 citations
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April 1999 in “British Journal of Dermatology” Keratin 2e shows a unique pattern in developing fetal skin, different from other keratins.
45 citations
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January 1986 15 citations
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January 1991 in “Mammalian Genome” 43 citations
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July 1994 in “Journal of Cell Science” Cross-linked proteins help maintain the structure of hair, feathers, and hagfish teeth.
2 citations
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October 1931 in “Archives of Dermatology and Syphilology” A rare scalp infection in a child developed into a kerion with additional skin symptoms.
53 citations
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June 1983 in “Journal of Investigative Dermatology” The enzyme is crucial for skin cell development and can be activated without proteolytic activation.
March 2009 in “Encyclopedia of Life Sciences” Mutations in keratin genes cause skin disorders, but new treatments show promise.
47 citations
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June 1994 in “Experimental Cell Research” mHa2 and mHa3 keratins have different structures and roles in mouse hair and tongue tissues.
287 citations
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July 2001 in “Journal of Cell Science” The study found 65 intermediate filament genes, including new keratins, and suggested updating keratin naming.
3 citations
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January 1984 21 citations
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June 2004 in “Experimental Dermatology” Ber‐EP4 marks cells related to the secondary hair germ in hair follicles.
January 2003 in “Jiepouxue zazhi” HHK can help restore skin structure.
72 citations
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September 1997 in “Journal of Investigative Dermatology”
22 citations
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August 2009 in “Evidence-based Complementary and Alternative Medicine” The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.
May 2004 in “International Journal of Cosmetic Science” Melanogenesis inhibitors like kojic acid and niacinamide can reduce inflammation and pigment production in skin cells.
Keratin gel may help repair damaged nerves.
186 citations
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December 2012 in “Current opinion in cell biology” Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
Brazilian keratin treatment can cause skin reactions like eczema.
6 citations
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September 2015 in “Journal of Investigative Dermatology” Using special RNA to target a mutant gene fixed hair problems in mice.
January 2012 in “Durham e-Theses (Durham University)” Keratin 15 affects cell behavior and characteristics in skin cells.
6 citations
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January 1985 in “ACTA HISTOCHEMICA ET CYTOCHEMICA” Tumor cells in calcifying epithelioma of Malherbe resemble hair follicle cells.
15 citations
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July 2004 in “Journal of morphology” Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.
75 citations
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October 1999 in “Differentiation” Mouse keratin 6 isoforms have different expression patterns in various tissues.
15 citations
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January 1988 Hair follicles have unique proteins that vary by species and are influenced by nutrition.
17 citations
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February 2015 in “Experimental Dermatology” Keratins are crucial for hair strength, and mutations in certain keratin genes cause hair disorders.
April 2023 in “Journal of Investigative Dermatology” Blocking casein kinase 1 in skin cells can help melanocyte precursors move better, potentially helping with conditions like vitiligo or gray hair.
2 citations
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December 2023 in “International journal of molecular sciences” Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.
18 citations
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April 2018 in “Biotechniques/BioTechniques” A new method was developed to extract and analyze proteins from very short human hairs.
18 citations
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June 1993 in “Archives of Dermatological Research” Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.
77 citations
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March 2000 in “Journal of Investigative Dermatology” The research identified six functional hair keratin genes and four pseudogenes, providing insights into hair formation and gene organization.