2 citations
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May 2023 in “Journal of Immunotherapy” Sintilimab treatment caused hair loss but led to complete tumor remission.
October 2022 in “Journal of pharmaceutical negative results” People with Alopecia areata have higher levels of certain T regulatory cells in their blood.
35 citations
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November 1989 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.
12 citations
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December 2017 in “Scientific reports” The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.
November 2025 in “Journal of Investigative Dermatology” Chronic refractory alopecia areata has more skin-resident memory T cells, and JAK inhibitors may help reduce them.
67 citations
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January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology” Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
December 2023 in “Paediatrics & Family Medicine/Pediatria & Medycyna Rodzinna” Type 1 diabetes patients often have other autoimmune diseases, which complicate their care.
May 2012 in “CRC Press eBooks” Some patients on anti-TNF drugs experience a type of hair loss called TAIAPA.
May 2025 in “The Journal of Rheumatology” SLE can cause unusual gastrointestinal symptoms, and immunosuppressive therapy can be effective.
November 2025 in “The Journal of Immunology” BTNL2 helps protect hair follicles from immune attacks, which could aid in treating alopecia areata.
July 2022 in “Journal of Investigative Dermatology” Inhibiting TYK2 can restore hair growth in alopecia areata.
8 citations
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July 1980 in “Archives of Dermatology” Hidden sweat gland tumors might cause hair loss.
7 citations
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December 2010 in “Current Drug Therapy” Anti-complement agents could effectively treat autoimmune diseases with fewer side effects.
January 2025 in “TURKDERM” Alopecia areata incognito in children can be effectively treated with triamcinolone acetonide and supplements, leading to full hair regrowth.
4 citations
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January 1989 in “Journal of Steroid Biochemistry” Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.
March 2026 in “Pediatrics in Review” The boy's symptoms improved with thyroid treatment, and he lost weight, but occasional palpitations persisted.
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January 2016 in “Pediatrics international” Japanese infants fed hydrolysate formula may have low biotin levels.
28 citations
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October 2010 in “Targeted Oncology” Trastuzumab may cause tufted hair folliculitis as a side effect.
1 citations
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November 2018 in “immuneACCESS” Expanded CD8+ T cells are linked to Alopecia Areata and may cause relapse after treatment.
2 citations
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June 2017 in “Psychiatry and clinical psychopharmacology” Stopping the antidepressant agomelatine improved hair loss in a patient.
April 2021 in “Anatolian current medical journal :” A patient developed hair loss after hepatitis C treatment with sofosbuvir and ribavirin.
September 2024 in “Cureus” Removing breast implants resolved the patient's symptoms.
March 2021 in “Research Square (Research Square)” Patients with RASopathies have a higher risk of autoimmune disorders and should be routinely screened.
14 citations
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August 2004 in “Veterinary Dermatology” The horse had a rare type of hair loss caused by immune cells attacking hair follicles.
143 citations
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May 2002 in “PubMed” LGD1069 effectively prevents breast tumors in mice without toxicity.
October 2021 in “Journal of Investigative Dermatology” Blocking IL-12 can help treat alopecia areata by preventing hair follicle immune issues.
16 citations
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February 1978 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Dihydrotestosterone specifically binds to hamster sebaceous glands, with a higher affinity than testosterone.
IL-18 signaling helps mature Tregs move into the thymus.
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August 2022 in “Cutis” Certain nail conditions can suggest thyroid problems, with different symptoms for underactive (slow, thin nails) and overactive (spoon-shaped, brittle nails) thyroid.
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April 2019 in “Journal of the Endocrine Society” Satoyoshi syndrome can occur without causing premature ovarian failure.