12 citations
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September 1990 in “The Anatomical Record” Human anagen hair follicles have unique carbohydrate patterns during keratinization.
115 citations
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November 2008 in “Proceedings of the National Academy of Sciences” Reptiles have genes similar to hair proteins, suggesting hair's genetic origins predate mammals.
32 citations
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January 2020 in “Journal of Molecular Histology” K31 can identify clear secretory cells in human sweat glands.
1 citations
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May 2004 in “Biochemical and Biophysical Research Communications” Two new gene clusters important for hair formation were found on human chromosome 11.
November 2025 in “PLoS ONE” Nucleic acids trigger chemokine production in skin cells, affecting skin inflammation.
January 2006 in “Chinese Journal of Dermatology” Amelanotic melanocytes from hair follicles are immature and likely don't transfer melanosomes to keratinocytes.
18 citations
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November 2005 in “Archives of Dermatological Research” 30 citations
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April 2009 in “Mycoses” Microsporum gypseum fungus breaks down keratin in hair by digesting it enzymatically, starting with less keratinized parts.
37 citations
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August 2000 in “Journal of Cutaneous Pathology” Poromas are related to sweat duct cells, and CK patterns help distinguish apocrine poromas from other neoplasms.
January 2007 in “Zhonghua shiyan waike zazhi” Basal layer skin cells help form the epidermis and hair follicles.
16 citations
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October 2014 in “Oral surgery, oral medicine, oral pathology and oral radiology” Keratoacanthoma comes from hair follicle cells.
April 2013 in “Cancer Research” SKH1 hairless mice have identifiable epidermal stem cells with specific markers.
30 citations
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January 1994 in “Micron” Mature hair surfaces are formed by keratinized cells with developed layers, not just modified plasma membranes.
133 citations
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March 1999 in “Journal of Cutaneous Pathology” Trichoepitheliomas and some basal cell carcinomas likely come from hair follicle stem cells.
14 citations
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July 1983 in “Acta Dermato Venereologica” A method was developed to grow millions of hair cells from a single hair for research and storage.
20 citations
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August 2017 in “PLoS ONE” 61 functional keratin genes were identified in dogs and horses, leading to updated gene annotations.
July 2016 in “Indian journal of science and technology” Neonate scalp hair is thinner, lacks a medulla, and has smaller follicles compared to adult hair.
29 citations
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July 2015 in “Journal of Medical Genetics” A genetic variant in the KRT25 gene causes tightly curled hair.
1 citations
,
October 2022 in “Veterinary pathology” Some canine hair follicle tumors contain amyloid deposits, with a protein called CK5 involved in their formation.
35 citations
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September 2004 in “American Journal of Dermatopathology” A rare nail bed cancer was successfully treated with no recurrence after 4 years.
December 2000 in “日本組織細胞化学会総会プログラムおよび抄録集”
38 citations
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October 2011 in “Analytical biochemistry” Hair proteins have weak spots in their α-helical segments.
49 citations
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October 1989 in “Genomics” Type I keratin genes are closely linked to the rex locus on mouse chromosome 11, affecting hair development.
29 citations
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February 1989 in “Journal of Cutaneous Pathology” A unique hair tumor with a rippled pattern was identified, showing incomplete differentiation and unusual cell arrangements.
14 citations
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May 2022 in “Stem cell reports” The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
8 citations
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April 2014 in “Clinical and Experimental Dermatology” Eruptive vellus hair cysts likely originate from the infrainfundibulum and sebaceous duct.
February 2024 in “Journal of Investigative Dermatology” Deleting NIPP1 in mouse skin cells causes early aging and chronic skin issues.
27 citations
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April 2004 in “Biochemical and Biophysical Research Communications” Two new gene clusters important for hair formation were found on human chromosome 11.
8 citations
,
January 2011 in “International journal of trichology” Accurate diagnosis of APL is crucial to avoid unnecessary treatments.
3 citations
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January 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin cells from people with Epidermolysis Bullosa Simplex have abnormally placed and less active mitochondria.